Transition Metal Complexes of New N-Amino Quinolone Derivative; Synthesis, Characterization, Thermal Study and Antimicrobial Properties

摘要

Schiff base ligand (H_2L) was synthesized by the condensation reaction of 2,4 - dihydroxy benzaldehyde and N - aminoquinolone- 2 - one in 1:1 molar ratio. The ligand which exhibits ONO donor set and transition metal complexes of Cr~(III), Fe~(III), Co~(II), Ni~(II) and Cu~(II) ions were synthesized and characterized by ~1HNMR, fourier transform infrared (FT-IR), UV - vis, elemental analysis, thermo gravimetric analysis (TGA), magnetic susceptibility and molar conductivity measurements. The ligand and metal complexes were evaluated for their anti bacterial activity using four strains of bacteria (two gram + and two gram -). The Cr~(III) and Cu~(II) complexes showed higher activity close to the control against all the tested organisms.