A randomised controlled trial of matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDITOF-MS) versus conventional microbiological methods for identifying pathogens: Impact on optimal antimicrobial therapy of invasive bacterial and fungal infections in Vietnam

Nadjm Behzad; Vu Quoc Dat; Campbell James I; Vu Tien Viet Dung; Torre Alessandro; Nguyen Thi Cam Tu; Ninh Thi Thanh Van; Dao Tuyet Trinh; Nguyen Phu Huong Lan; Nguyen Vu Trung; Nguyen Thi Thuy Hang; Le Thi Hoi; Baker Stephen; Wolbers Marcel; Nguyen Van Vinh Chau; Nguyen Van Kinh; Thwaites Guy E.; van Doorn H. Rogier; Wertheim Heiman F. L.

首页> 外文期刊>Journal of Infection >A randomised controlled trial of matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDITOF-MS) versus conventional microbiological methods for identifying pathogens: Impact on optimal antimicrobial therapy of invasive bacterial and fungal infections in Vietnam

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A randomised controlled trial of matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDITOF-MS) versus conventional microbiological methods for identifying pathogens: Impact on optimal antimicrobial therapy of invasive bacterial and fungal infections in Vietnam

机译：用于鉴定病原体的基质辅助激光解吸电离 - 飞行质谱（Malditof-MS）的随机对照试验与常规微生物方法的常规微生物学方法：对越南侵袭性细菌和真菌感染的最佳抗微生物治疗的影响

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Objectives: We assessed the impact of MALDITOF-MS on the timeliness of optimal antimicrobial therapy through a parallel-arm randomised controlled trial in two hospitals in Vietnam.

机译：目的：我们通过两家医院在越南的两家医院的平行臂随机对照试验评估了MALDITOF-MS对最佳抗微生物治疗的及时性的影响。

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来源
《Journal of Infection》 |2019年第6期|共7页
作者
Nadjm Behzad; Vu Quoc Dat; Campbell James I; Vu Tien Viet Dung; Torre Alessandro; Nguyen Thi Cam Tu; Ninh Thi Thanh Van; Dao Tuyet Trinh; Nguyen Phu Huong Lan; Nguyen Vu Trung; Nguyen Thi Thuy Hang; Le Thi Hoi; Baker Stephen; Wolbers Marcel; Nguyen Van Vinh Chau; Nguyen Van Kinh; Thwaites Guy E.; van Doorn H. Rogier; Wertheim Heiman F. L.;
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作者单位

Univ Oxford Clin Res Unit Hanoi Vietnam;

Univ Oxford Clin Res Unit Hanoi Vietnam;

Univ Oxford Clin Res Unit Hanoi Vietnam;

Univ Oxford Clin Res Unit Hanoi Vietnam;

Univ Oxford Clin Res Unit Hanoi Vietnam;

Univ Oxford Clin Res Unit Hanoi Vietnam;

Univ Oxford Clin Res Unit Hanoi Vietnam;

Natl Hosp Trop Dis Hanoi Vietnam;

Hosp Trop Dis Ho Chi Minh City Vietnam;

Natl Hosp Trop Dis Hanoi Vietnam;

Natl Hosp Trop Dis Hanoi Vietnam;

Natl Hosp Trop Dis Hanoi Vietnam;

Univ Oxford Clin Res Unit Hanoi Vietnam;

Univ Oxford Clin Res Unit Hanoi Vietnam;

Hosp Trop Dis Ho Chi Minh City Vietnam;

Natl Hosp Trop Dis Hanoi Vietnam;

Univ Oxford Clin Res Unit Hanoi Vietnam;

Univ Oxford Clin Res Unit Hanoi Vietnam;

Univ Oxford Nuffield Dept Clin Med Ctr Trop Med &

Global Hlth Oxford England;

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原文格式 PDF
正文语种 eng
中图分类传染病;
关键词
Matrix-assisted laser desorption-ionization mass spectrometry; Microbiological techniques; Bacteraemia; Antibacterial agents; Vietnam;

机译：基质辅助激光解吸 - 电离质谱;微生物技术;菌血症;抗菌剂;越南;

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专利

1. A randomised controlled trial of matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDITOF-MS) versus conventional microbiological methods for identifying pathogens: Impact on optimal antimicrobial therapy of invasive bacterial and fungal infections in Vietnam [J] . Nadjm Behzad, Vu Quoc Dat, Campbell James I, Journal of Infection . 2019,第6期

机译：用于鉴定病原体的基质辅助激光解吸电离 - 飞行质谱（Malditof-MS）的随机对照试验与常规微生物方法的常规微生物学方法：对越南侵袭性细菌和真菌感染的最佳抗微生物治疗的影响
2. Rapid identification of pathogens directly from blood culture bottles by Bruker matrix-assisted laser desorption laser ionization-time of flight mass spectrometry versus routine methods [J] . JamalW., SaleemR., RotimiV.O. Diagnostic microbiology and infectious disease . 2013,第4期

机译：布鲁克基质辅助激光解吸激光电离飞行时间质谱与常规方法直接从血液培养瓶中快速鉴定病原体
3. High-Throughput Identification of Bacteria and Yeast by Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry in Conventional Medical Microbiology Laboratories [J] . S. Q. van Veen, E. C. J. Claas, Ed J. Kuijper Journal of Clinical Microbiology . 2010,第3期

机译：常规医学微生物实验室中基质辅助激光解吸电离-飞行时间质谱法高通量鉴定细菌和酵母
4. Optimization of Sample Preparation for Detection of Common Food-borne Pathogens by Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry [C] . Lay Hoon Seah, Tze Horng Liew, Aldrich Leow, ASMS Conference on Mass Spectrometry and Allied Topics . 2015

机译：通过基质辅助激光解吸电离 - 飞行质谱法检测常见食品传播病原体的样品制剂的优化
5. Nonpolar matrices for matrix-assisted laser desorption/ionization-time of flight-mass spectrometry. [D] . Robins, Chad LaJuan. 2005

机译：非极性矩阵用于基质辅助激光解吸/电离飞行时间质谱。
6. A randomised controlled trial of matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDITOF-MS) versus conventional microbiological methods for identifying pathogens: Impact on optimal antimicrobial therapy of invasive bacterial and fungal infections in Vietnam [O] . Behzad Nadjm, Vu Quoc Dat, James I. Campbell, -1

机译：基质辅助激光解吸电离飞行时间质谱（MALDITOF-MS）与常规微生物学方法鉴定病原体的随机对照试验：对越南侵袭性细菌和真菌感染的最佳抗菌治疗的影响
7. High-Throughput Identification of Bacteria and Yeast by Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry in Conventional Medical Microbiology Laboratories ▿ [O] . van Veen, S. Q., Claas, E. C. J., Kuijper, Ed J. 2010

机译：常规医学微生物学实验室中基质辅助激光解吸电离-飞行时间质谱技术对细菌和酵母的高通量鉴定

A randomised controlled trial of matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDITOF-MS) versus conventional microbiological methods for identifying pathogens: Impact on optimal antimicrobial therapy of invasive bacterial and fungal infections in Vietnam

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