The effect of gut microbiota and probiotic organisms on the properties of extended spectrum beta-lactamase producing and carbapenem resistant Enterobacteriaceae including growth, beta-lactamase activity and gene transmissibility

摘要

The gut microbiota may play a pivotal role in controlling the antimicrobial resistant (AMR) organisms although the evidences are limited. We investigated the effects of gut microbiota on the growth of AMR organisms, beta-lactamases activity and transmissibility of antimicrobial resistant properties of the extended spectrum beta-lactamase (ESBL)-producing Escherichia coli and carbapenem-resistant Enterobacteriaceae.