Multicomponent Efficient Synthesis of New [1,2,4]Triazolo[3,4]thiadiazines

摘要

A series of novel triazolo thiadiazines were synthesized by a simple, highly efficient, one-pot pseudo four component approach involving the condensation of 4-amino-5-hydrazinyl-4H-1,2,4-triazole-3-thiol (1), aromatic aldehydes (2), and various phenacyl bromides (3) with good yields. The structures of compounds were confirmed by analytical and spectral (IR, H-1 NMR, C-13 NMR) data.