A clinical study assessing the short-term efficacy of combined in-office/at-home whitening treatment

摘要

Objective The purpose of this randomized clinical trial was to assess the efficacy of color change in combined in-office/at-home whitening. Materials and Methods Thirty participants were randomly divided into two groups: 15 received combined treatment in-office whitening (6% hydrogen peroxide + 2 weeks at-home whitening with 16% carbamide peroxide [CP]); 15 were assigned to control group. Instrumental color measurements were obtained before whitening (t(0)), immediately after in-office whitening (t(in-office)), after 1 week of active treatments (t(1)), and at the completion of the whitening treatment (t(2)). CIE L*a*b* values were recorded and CIE L*a*b* and CIEDE2000 color differences were calculated. Results The color change at t(in-office) was Delta E-ab = 4.7 and Delta E-00 = 3.2 and overall color change of combined method at t(2) was Delta E-ab = 8.2 and Delta E-00 = 5.3 (P < 0.05). A statistically significant effect for the mean CIE L*a*b* and CIEDE2000 values was detected within time with the mean a*, b* and C ' values decreasing and mean h ' values increasing significantly (P < 0.05). Conclusions Combined in-office/at-home whitening was effective. Whitening efficacy increased upon application of 16% CP in combined in-office/at-home treatment (P < 0.05). Clinical Significance The statistically significant increase in color change recommends clinical application of combined in-office/at-home whitening treatment.