Effect of phacoemulsification incision size on incision repair and remodeling: Optical coherence tomography assessment

摘要

PurposeTo characterize the effect of incision size on corneal incision repair and remodeling over 3?months after cataract surgery. SettingDepartment of Ophthalmology, Auckland District Health Board, Auckland, New Zealand. DesignProspective case series. MethodsEyes having routine cataract surgery were randomized to receive 2.20?mm or 2.85?mm uniplanar clear corneal incisions. Anterior segment optical coherence tomography of incision thickness, length, width, gaping, and angle and specular microscopy of endothelial cell density (ECD), polymegathism, and pleomorphism were completed at baseline and 1, 7, 30, and 90?days postoperatively. ResultsEach incision group comprised 50 eyes (50 patients). Ninety-nine patients (99%) attended all assessments. The Descemet membrane detachment rate was greater than 50% with 2.20?mm incisions (P?=?.01). Patients with Descemet membrane detachments had increased endothelial wound gaping, slower visual recovery, and increased corneal thickness at the incision site at all visits (Φ?=?0.54,P?