HIV-1 non-R5 tropism correlates with a larger size of the cellular viral reservoir and a detectable residual viremia in patients under suppressive ART

Lombardi Francesca; Belmonti Simone; Rapone Lucrezia; Borghetti Alberto; Ciccullo Arturo; Gagliardini Roberta; Baldin Gianmaria; Montagnani Francesca; Moschese Davide; Emiliozzi Arianna; Rossetti Barbara; De Luca Andrea; Di Giambenedetto Simona

首页> 外文期刊>Journal of clinical virology: The official publication of the Pan American Society for Clinical Virology >HIV-1 non-R5 tropism correlates with a larger size of the cellular viral reservoir and a detectable residual viremia in patients under suppressive ART

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HIV-1 non-R5 tropism correlates with a larger size of the cellular viral reservoir and a detectable residual viremia in patients under suppressive ART

机译：HIV-1非R 5对抗热衷于抑制艺术患者的细胞病毒储层和可检测的残余病毒血症相关性

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Background: The influence of HIV-1 co-receptor usage on the course of therapy in subjects fully responding to ART has been poorly investigated.

机译：背景：HIV-1共同受体使用对受试者完全响应艺术的疗法的影响已经令人难以理解。

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来源
《Journal of clinical virology: The official publication of the Pan American Society for Clinical Virology》 |2018年第2018期|共6页
作者
Lombardi Francesca; Belmonti Simone; Rapone Lucrezia; Borghetti Alberto; Ciccullo Arturo; Gagliardini Roberta; Baldin Gianmaria; Montagnani Francesca; Moschese Davide; Emiliozzi Arianna; Rossetti Barbara; De Luca Andrea; Di Giambenedetto Simona;
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作者单位

Univ Cattolica Sacro Cuore Inst Clin Infect Dis Largo Agostino Gemelli 8 I-00168 Rome Italy;

Univ Cattolica Sacro Cuore Inst Clin Infect Dis Largo Agostino Gemelli 8 I-00168 Rome Italy;

Univ Cattolica Sacro Cuore Inst Clin Infect Dis Largo Agostino Gemelli 8 I-00168 Rome Italy;

Univ Cattolica Sacro Cuore Inst Clin Infect Dis Largo Agostino Gemelli 8 I-00168 Rome Italy;

Univ Cattolica Sacro Cuore Inst Clin Infect Dis Largo Agostino Gemelli 8 I-00168 Rome Italy;

Univ Cattolica Sacro Cuore Inst Clin Infect Dis Largo Agostino Gemelli 8 I-00168 Rome Italy;

Univ Cattolica Sacro Cuore Inst Clin Infect Dis Largo Agostino Gemelli 8 I-00168 Rome Italy;

Siena Univ Hosp Univ Div Infect Dis Dept Specialized &

Internal Med Viale Bracci 16 I-53100;

Univ Cattolica Sacro Cuore Inst Clin Infect Dis Largo Agostino Gemelli 8 I-00168 Rome Italy;

Univ Cattolica Sacro Cuore Inst Clin Infect Dis Largo Agostino Gemelli 8 I-00168 Rome Italy;

Siena Univ Hosp Univ Div Infect Dis Dept Specialized &

Internal Med Viale Bracci 16 I-53100;

Siena Univ Hosp Univ Div Infect Dis Dept Specialized &

Internal Med Viale Bracci 16 I-53100;

Univ Cattolica Sacro Cuore Inst Clin Infect Dis Largo Agostino Gemelli 8 I-00168 Rome Italy;

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原文格式 PDF
正文语种 eng
中图分类医学微生物学（病原细菌学、病原微生物学）;
关键词
Virological suppression; ART; HIV-1 tropism; HIV-1 DNA; HIV-1 residual viremia;

机译：病毒学抑制;艺术;HIV-1热衷;HIV-1 DNA;HIV-1残留的病毒血症;

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专利

1. HIV-1 non-R5 tropism correlates with a larger size of the cellular viral reservoir and a detectable residual viremia in patients under suppressive ART [J] . Lombardi Francesca, Belmonti Simone, Rapone Lucrezia, Journal of clinical virology: The official publication of the Pan American Society for Clinical Virology . 2018,第期

机译：HIV-1非R 5对抗热衷于抑制艺术患者的细胞病毒储层和可检测的残余病毒血症相关性
2. The temporal increase in HIV-1 non-R5 tropism frequency among newly diagnosed patients from northern Poland is associated with clustered transmissions [J] . Mi?osz Parczewski, Magdalena Leszczyszyn-Pynka, Magdalena Witak-J?dra, Journal of the International Aids Society . 2015,第1期

机译：在波兰北部新诊断的患者中，HIV-1非R5嗜性频率随时间的增加与传播聚集有关
3. Temporal increase in HIV-1 non-R5 tropism frequency among antiretroviral-naive patients from northern Poland [J] . Milosz Parczewski, Magdalena Leszczyszyn-Pynka, Magdalena Witak-Jêdra, Journal of the International Aids Society . 2014,第4Suppla3期

机译：来自波兰北部的抗逆转录病毒初治患者中HIV-1非R5嗜性频率的时间增加
4. Genetic Diversity of RT-SHIV Viremia and Viral Reservoirs in a Non-human Primate Model of Human HIV-1 Highly Active Antiretroviral Therapy. [D] . Kauffman, Robert Clark. 2014

机译：RT-SHIV病毒血症和病毒库的遗传多样性在人类HIV-1高效抗逆转录病毒疗法的非人类灵长类动物模型中。
5. Identification of Ongoing Human Immunodeficiency Virus Type 1 (HIV-1) Replication in Residual Viremia during Recombinant HIV-1 Poxvirus Immunizations in Patients with Clinically Undetectable Viral Loads on Durable Suppressive Highly Active Antiretroviral Therapy [O] . Carlum Shiu, Coleen K. Cunningham, Thomas Greenough, 2009

机译：在持续抑制性高活性抗逆转录病毒疗法无法检测到病毒载量的重组HIV-1痘病毒免疫期间在残留病毒血症中鉴定正在进行的人类免疫缺陷病毒1型（HIV-1）复制
6. Identification of Ongoing Human Immunodeficiency Virus Type 1 (HIV-1) Replication in Residual Viremia during Recombinant HIV-1 Poxvirus Immunizations in Patients with Clinically Undetectable Viral Loads on Durable Suppressive Highly Active Antiretroviral Therapy▿ [O] . Shiu, Carlum, Cunningham, Coleen K., Greenough, Thomas, 2009

机译：在持续抑制性高活性抗逆转录病毒疗法无法临床检测到病毒载量的重组HIV-1痘病毒免疫期间，在残留病毒血症中鉴定正在进行的人类免疫缺陷病毒1型（HIV-1）复制

HIV-1 non-R5 tropism correlates with a larger size of the cellular viral reservoir and a detectable residual viremia in patients under suppressive ART

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