首页> 外文期刊>Journal of Chemical Technology & Biotechnology >Using a combined oxygen‐supply and substrate‐feeding strategy to improve 2,3‐butanediol production by metabolically engineered Klebsiella oxytocaKlebsiella oxytoca KMS005

【24h】

Using a combined oxygen‐supply and substrate‐feeding strategy to improve 2,3‐butanediol production by metabolically engineered Klebsiella oxytocaKlebsiella oxytoca KMS005

机译：使用组合的氧气供应和衬底喂养策略来通过代谢工程化学改善2,3-丁二醇生成 Klebsiella oxytoca Klebsiella oxytoca KMS005.

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Abstract <section xml:id="jctb5409-sec-0001" numbered="no"> <title type="main">BACKGROUND > There is much demand for and extensive application for 2,3‐butanediol (2,3‐BD) in various fields, and micro‐aerobic and substrate‐feeding conditions greatly affect microbial growth and production. The theoretical maximum of 2,3‐BD fermentative yield has rarely been reported. Therefore, our study aimed to develop an efficient combined oxygen‐supply and substrate‐feeding strategy to improve 2,3‐BD production yield in metabolically engineered <fi>Klebsiella oxytoca</fi> KMS005. </section> <section xml:id="jctb5409-sec-0002" numbered="no"> <title type="main">RESULTS > The optimized oxygen consumption for 2,3‐BD production by strain KMS005 was demonstrated at 9.2 g for 1 L working volume corresponding to KLa of 25.2 h ?1 . During fed‐batch, a glucose feeding rate of 2 g h ?1 starting at the end of the growth phase for 48 h followed by a final batch phase of 40 h was found likely to be satisfactory for 2,3‐BD production by the strain KMS005. A final 2,3‐BD concentration was obtained at 74.7 g L ?1 with few by‐products formation. A theoretical maximum of 2,3‐BD production yield of 0.5 g g ?1 substrate used was also approached. </section> <section xml:id="jctb5409-sec-0003" numbered="no"> <title type="main">CONCLUSION > Our oxygen‐supply strategy with the specific feeding pattern developed in this study allowed the highest fermentative production yield of 2,3‐BD ever reported. The KMS005 strain may be used as a biocatalyst fo </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> <div class="translation abstracttxt"> <span class="zhankaihshouqi fivelineshidden" id="abstract"> <span>机译：</span><Abstract XMLNS =“http://www.wiley.com/namespaces/wiley”type =“main”xml：lang =“en”> <title type =“main”>抽象</ title> <section XML：ID =“JCTB5409-SEC-0001”编号=“否”> <标题类型=“main”>背景</ title> >对于2,3-丁烷二醇有很多需求和广泛的应用（2,3-BD ）在各个领域，微食和底物喂养条件极大地影响微生物生长和生产。很少报道了2,3-BD发酵产率的最大值。因此，我们的研究旨在开发有效的组合氧气供应和基材供给策略，以提高代谢工程化的2,3-BD产量<Fi> Klebsiella催产症</ Fi> KMS005。 </ p> </ section> <section XML：ID =“JCTB5409-SEC-0002”编号=“否”> <标题类型=“main”>结果</ title> > 2的优化氧气消耗，通过应变KMS005的3-BD产生以9.2g，对应于25.2小时的KLA的1μg工作体积。在批量生期间，在生长阶段结束时，葡萄糖进料速率为2GH 1 </ sup> 48小时，然后发现40小时的最终分批阶段可能是令人满意的， 3-BD由菌株KMS005产生。在74.7g l 1 / sup>，含有副产物的形成，获得最终的2,3-bd浓度。还接近使用0.5g g α1</ sup>衬底的理论最大值。 </ p> </ section> <section XML：ID =“JCTB5409-SEC-0003”编号=“否”> <标题类型=“main”>结论</ title> >我们的氧气供应策略在本研究中开发的特定饲养模式允许曾有2,3-BD的最高发酵产量。 KMS005菌株可用作生物催化剂 </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> </div> <div class="record"> <h2 class="all_title" id="enpatent33" >著录项</h2> <ul> <li> <span class="lefttit">来源</span> <div style="width: 86%;vertical-align: text-top;display: inline-block;"> <a href='/journal-foreign-33908/'>《Journal of Chemical Technology & Biotechnology》</a> <b style="margin: 0 2px;">|</b><span>2018年第2期</span><b style="margin: 0 2px;">|</b><span>共9页</span> </div> </li> <li> <div class="author"> <span class="lefttit">作者</span> <p id="fAuthorthree" class="threelineshidden zhankaihshouqi"> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Chan Sitha&option=202" target="_blank" rel="nofollow">Chan Sitha;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Kanchanatawee Sunthorn&option=202" target="_blank" rel="nofollow">Kanchanatawee Sunthorn;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Jantama Sirima Suvarnakuta&option=202" target="_blank" rel="nofollow">Jantama Sirima Suvarnakuta;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Jantama Kaemwich&option=202" target="_blank" rel="nofollow">Jantama Kaemwich;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Joannis‐Cassan Claire&option=202" target="_blank" rel="nofollow">Joannis‐Cassan Claire;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Taillandier Patricia&option=202" target="_blank" rel="nofollow">Taillandier Patricia;</a> </p> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zkzz" style="display: none;">展开▼</span> </div> </li> <li> <div style="display: flex;"> <span class="lefttit">作者单位</span> <div style="position: relative;margin-left: 3px;max-width: 639px;"> <div class="threelineshidden zhankaihshouqi" id="fOrgthree"> <p>Institute of Agricultural TechnologySuranaree University of TechnologyNakhon Ratchasima Thailand;</p> <p>Institute of Agricultural TechnologySuranaree University of TechnologyNakhon Ratchasima Thailand;</p> <p>Faculty of Pharmaceutical SciencesUbon Ratchathani UniversityUbon Ratchathani Thailand;</p> <p>Institute of Agricultural TechnologySuranaree University of TechnologyNakhon Ratchasima Thailand;</p> <p>Laboratory of Chemical EngineeringUniversité de ToulouseToulouse France;</p> <p>Laboratory of Chemical EngineeringUniversité de ToulouseToulouse France;</p> </div> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zhdw" style="display: none;">展开▼</span> </div> </div> </li> <li > <span class="lefttit">收录信息</span> <span style="width: 86%;vertical-align: text-top;display: inline-block;"></span> </li> <li> <span class="lefttit">原文格式</span> <span>PDF</span> </li> <li> <span class="lefttit">正文语种</span> <span>eng</span> </li> <li> <span class="lefttit">中图分类</span> <span><a href="https://www.zhangqiaokeyan.com/clc/180.html" title="生物工程学（生物技术）">生物工程学（生物技术）;</a><a href="https://www.zhangqiaokeyan.com/clc/20827.html" title="生物化学过程">生物化学过程;</a></span> </li> <li class="antistop"> <span class="lefttit">关键词</span> <p style="width: 86%;vertical-align: text-top;"> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=biocatalysis&option=203" rel="nofollow">biocatalysis;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=aeration&option=203" rel="nofollow">aeration;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=fermentation&option=203" rel="nofollow">fermentation;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=metabolic engineering&option=203" rel="nofollow">metabolic engineering;</a> </p> <div class="translation"> 机译：生物分析;曝气;发酵;代谢工程; </div> </li> </ul> </div> </div> <div class="literature cardcommon"> <div class="similarity "> <h3 class="all_title" id="enpatent66">相似文献</h3> <div class="similaritytab clearfix"> <ul> <li class="active" >外文文献</li> <li >专利</li> </ul> </div> <div class="similarity_details"> <ul > <li> <div> <b>1. </b><a class="enjiyixqcontent" href="/journal-foreign-detail/0704025422696.html">Using a combined oxygen‐supply and substrate‐feeding strategy to improve 2,3‐butanediol production by metabolically engineered <fi xmlns="http://www.wiley.com/namespaces/wiley">Klebsiella oxytoca</fi>Klebsiella oxytoca KMS005</a> <b>[J]</b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Chan Sitha&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Chan Sitha,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Kanchanatawee Sunthorn&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Kanchanatawee Sunthorn,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Jantama Sirima Suvarnakuta&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Jantama Sirima Suvarnakuta,</a> <a href="/journal-foreign-33908/" target="_blank" rel="nofollow" class="tuijian_authcolor">Journal of Chemical Technology & Biotechnology .</a> <span>2018</span><span>,第2期</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：使用组合的氧气供应和衬底喂养策略来通过代谢工程化学改善2,3-丁二醇生成<fi xmlns =“http://www.wiley.com/namespaces/wiley”> Klebsiella oxytoca </ Fi> Klebsiella oxytoca KMS005.</span> </p> </li> <li> <div> <b>2. </b><a class="enjiyixqcontent" href="/journal-foreign-detail/0704025422647.html">Effect of fluid dynamic conditions on 2,3‐butanediol production by <fi xmlns="http://www.wiley.com/namespaces/wiley">Raoultella terrigena</fi>Raoultella terrigena in <fc xmlns="http://www.wiley.com/namespaces/wiley">SBTR</fc>SBTR : oxygen transfer and uptake rates</a> <b>[J]</b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Rodriguez Alberto&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Rodriguez Alberto,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Ripoll Vanessa&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Ripoll Vanessa,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Santos Victoria E&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Santos Victoria E,</a> <a href="/journal-foreign-33908/" target="_blank" rel="nofollow" class="tuijian_authcolor">Journal of Chemical Technology & Biotechnology .</a> <span>2017</span><span>,第6期</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：<fi xmlns =“http://www.wiley.com/namespaces/wiley”> Raoultella Terrigena </ Fi> Raoultella Terrigena在<FC XMLNS =“http：/ /www.wiley.com/namespaces/wiley">sbtr</fc postbtr：氧气转移和摄取率</span> </p> </li> <li> <div> <b>3. </b><a class="enjiyixqcontent" href="/journal-foreign-detail/0704023566543.html">A projection‐based algorithm for <fi xmlns="http://www.wiley.com/namespaces/wiley">?</fi>? <sub xmlns="http://www.wiley.com/namespaces/wiley">2</sub>2 ‐ <fi xmlns="http://www.wiley.com/namespaces/wiley">?</fi>? <sub xmlns="http://www.wiley.com/namespaces/wiley"> <fi>p</fi> </sub> <fi xmlns="http://www.wiley.com/namespaces/wiley">p</fi>p Tikhonov regularization</a> <b>[J]</b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Borges Leonardo S.&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Borges Leonardo S.,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Bazán Fermín S.V.&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Bazán Fermín S.V.,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Bedin Luciano&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Bedin Luciano </a> <a href="/journal-foreign-24473/" target="_blank" rel="nofollow" class="tuijian_authcolor">Mathematical Methods in the Applied Sciences .</a> <span>2018</span><span>,第15期</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：基于投影的<fi xmlns =“http://www.wiley.com/namespaces/wiley”>？</ fi>的投影算法？ <sub xmlns =“http://www.wiley.com/namespaces/wiley”> 2 </ sub> 2 - <fi xmlns =“http://www.wiley.com/namespaces/wiley”>？</ fi>？ <sub xmlns =“http://www.wiley.com/namespaces/wiley”> <fi> p </ fi> </ sub> <fi xmlns =“http://www.wiley.com/namespaces/wiley “> P </ FI> P TIKHONOV规则</span> </p> </li> <li> <div> <b>4. </b><a class="enjiyixqcontent" href="/academic-conference-foreign_meeting-190212_thesis/020512873376.html">Production of 2,3-Butanediol from Pretreated Corn Cob by Klebsiella oxytoca in the Presence of Fungal Cellulase</a> <b>[C]</b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=NINGJUN CAO&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">NINGJUN CAO,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=YOUKUN XIA&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">YOUKUN XIA,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=CHENG S. GONG&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">CHENG S. GONG,</a> <a href="/conference-foreign-190212/" target="_blank" rel="nofollow" class="tuijian_authcolor">Biotechnology for Fuels and Chemicals .</a> <span>1997</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：在真菌纤维素酶作用下，氧化克雷伯菌从预处理的玉米芯生产2,3-丁二醇</span> </p> </li> <li> <div> <b>5. </b><a class="enjiyixqcontent" href="/academic-degree-foreign_mphd_thesis/02061500798.html">Experimental study and mathematical modeling of immobilized Klebsiella oxytoca for 2,3-butanediol production.</a> <b>[D] </b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Lo, Waihung.&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Lo, Waihung. </a> <span>1991</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：固定化产克雷伯菌产2,3-丁二醇的实验研究和数学模型。</span> </p> </li> <li> <div> <b>6. </b><a class="enjiyixqcontent" href="/academic-journal-foreign-pmc_detail_thesis/040005410096.html">Process Optimization on Micro-Aeration Supply for High Production Yield of 23-Butanediol from Maltodextrin by Metabolically-Engineered Klebsiella oxytoca</a> <b>[O] </b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Sitha Chan&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Sitha Chan,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Sirima Suvarnakuta Jantama&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Sirima Suvarnakuta Jantama,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Sunthorn Kanchanatawee&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Sunthorn Kanchanatawee,</a> <span>-1</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：代谢工程产克雷伯菌的微曝气工艺优化从麦芽糖糊精高产23-丁二醇</span> </p> </li> <li> <div> <b>7. </b><a class="enjiyixqcontent" href="/open-access_resources_thesis/01000128647203.html">Using a combined oxygen-supply and substrate-feeding strategy to improve 2,3-butanediol production by metabolically engineered Klebsiella oxytoca KMS005</a> <b>[O] </b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Sitha Chan&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Sitha Chan,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Sunthorn Kanchanatawee&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Sunthorn Kanchanatawee,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Sirima Suvarnakuta Jantama&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Sirima Suvarnakuta Jantama,</a> <span>2017</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：使用组合的氧气供应和基材供给策略通过代谢工程化的Klebsiella oxytoca KMS005改善2,3-丁二醇生产</span> </p> </li> </ul> <ul style="display: none;"> <li> <div> <b>1. </b><a class="enjiyixqcontent" href="/patent-detail/06130422003971.html">KLEBSIELLA OXYTOCA M 1 HAVING A SUPERIOR PRODUCTION YIELD OF 2,3- BUTANEDIOL</a> <b>[P]</b> . <span> 外国专利：  KR20120096755A </span> <span> . 2012-08-31</span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：KLEBSIELLA OXYTOCA M 1具有2,3-丁二醇的优异产量 </span> </p> </li> </ul> </div> </div> </div> <div class="theme cardcommon" style="overflow: auto;display:none"> <h3 class="all_title" id="enpatent55">相关主题</h3> <ul id="subject"> </ul> </div> </div> </div> </div> <div class="right rightcon"> <div class="details_img cardcommon clearfix" style="margin-bottom: 10px;display:none;" > </div> </div> </div> <div id="thesis_get_original1" class="downloadBth" style="bottom: 19px;z-index: 999;" onclick="ywcd('0704025422696','4',7,2,1,'',this,24)" class="delivery" prompt="010401" title="通过人工服务将文献原文发送至邮箱" >获取原文</div> <div class="journalsub-pop-up" style="display: none"> <div class="journal-sub"> <h2>期刊订阅</h2> <img src="https://cdn.zhangqiaokeyan.com/img/loginclose.png" alt="" onclick="$('.journalsub-pop-up').hide()"> <p class="pardon">抱歉，该期刊暂不可订阅，敬请期待！</p> <p class="current">目前支持订阅全部北京大学中文核心（2020）期刊目录。</p> <div style="display: flex;margin-top: 69px;justify-content: space-between;"> <div class="no-sub" onclick="$('.journalsub-pop-up').hide()">暂不订阅</div> <div class="other-sub" onclick="continueSub('from=pc-detail')">继续订阅其他期刊</div> </div> </div> </div> <div class="right_btn"> <ul> <li class="gouwuche">  </li> <li class="yijian"> <a href="javascript:void(0);" onclick="link_analysis('/mycenter/auth/complaint.html',this)">意见反馈</a> </li> <li class="top"> <a href="javascript:scrollTo(0,0);">回到顶部</a> </li> <li class="shouye"> <a href="/">回到首页</a> </li> </ul> </div> <div class="xllindexfooter"> <div class="xllindexfootercenter"> <div class="xllindexfooterleft left" > <div class="xllindexfooterleftli"> <ul> <li><a href="/about.html">关于掌桥</a></li> <li><a href="/help/helpmap.html">资源导航</a></li> <li><a href="/help/helpguide.html">新手指南</a></li> <li><a href="/help/helpcenter.html">常见问题</a></li> <li><a href="/sitemap.html">网站地图</a></li> <li><a href="/help/helpcenter.html?type=9">版权声明</a></li> </ul> </div> <div class="xllindexfooterleft"> <p class="xllindexfooterlefteamil">客服邮箱：kefu@zhangqiaokeyan.com</p> <div class="xllindexfooterlefttcp"> <div class="xllindexfooterpoliceiimg"></div> <div class="xllindexfooterpoliceispan"> <span>京公网安备：11010802029741号 </span> <span>ICP备案号：<a href="https://beian.miit.gov.cn" rel="nofollow" target="_blank">京ICP备15016152号-6</a></span> <span>六维联合信息科技 (北京) 有限公司©版权所有</span> </div> </div> </div> </div> <div class="xllindexfooterright left"> <ul> <li> <p style="font-weight: bold;">客服微信</p> <div></div> </li> <li> <p style="font-weight: bold;">服务号</p> <div></div> </li> </ul> </div> </div> </div> <span id="0704025422696down" data-source="7," data-out-id="Vj/yc54rd3T5GKRtT//X5w==," data-f-source-id="7" data-title="Using a combined oxygen‐supply and substrate‐feeding strategy to improve 2,3‐butanediol production by metabolically engineered <fi xmlns='http://www.wiley.com/namespaces/wiley'>Klebsiella oxytoca</fi>Klebsiella oxytoca KMS005" data-price="20" data-site-name="" data-transnum="24" style="display:none;"></span> <input type="hidden" value="4" id="sourcetype"> <input type="hidden" value="33908" id="journalid"> <input type="hidden" value="1" id="inyn_provide_service_level"> <input type="hidden" value="https://cdn.zhangqiaokeyan.com" id="imgcdn"> <input type="hidden" value="1" id="isdeatail"> <input type="hidden" value="" id="syyn_indexed_database"> <input type="hidden" value="" id="servicetype"> <input type="hidden" id="pagename" value="Using a combined oxygen‐supply and substrate‐feeding strategy to improve 2,3‐butanediol production by metabolically engineered <fi xmlns='http://www.wiley.com/namespaces/wiley'>Klebsiella oxytoca</fi>Klebsiella oxytoca KMS005"/> <input type="hidden" value="thesis_get_original" id="pageIdentification"> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/jquery-1.12.4.js"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/common/lwlh_ajax.js"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/zq.js?v=5.7.7"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/common/common.js?v=5.7.7"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/jquery.cookie.js"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/top.js?v=5.7.7"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/common/tip.js?v=5.7.7"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/common/login.js?v=5.7.7"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/common/down.js?v=5.7.7"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/common/search.js?v=5.7.7"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/searchtype.js?v=5.7.7"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/user/regist.js?v=5.7.7"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/zxs_solor/detail.js?v=5.7.7"></script> <script type="text/javascript" src="https://www.zhangqiaokeyan.com/statistics/static/pagecollection.js"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/tj.js"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/pushbaidu.js"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/common/history.js"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/util/cookie.js?v=5.7.7"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/weipu/weipu.js?v=5.7.7"></script> </body> <script> $(function(){ var weiPuStatus = getCookie('WeiPuStatus'); if(weiPuStatus){ tipWeiPuStatus(weiPuStatus); delCookie('WeiPuStatus'); } getFacetKeywordVoInId(); var sourcetype = $("#sourcetype").val(); var inyn_provide_service_level = $("#inyn_provide_service_level").val(); if((sourcetype ==1||sourcetype==4)&&inyn_provide_service_level!=4){ getJournal(); } }) </script> </html>