Two photons for closing blood vessels

摘要

Oxford (UK) - The spatial control of optical absorption provided by two-photon excitation holds particular promise for the targeted closure of blood vessels associated with neoplastic diseases, especially for the treatment of complex organs such as the eye or brain, where high spatial selectivity is crucial. Now, for the first time, researchers were able to demonstrate in vivo photody-namic therapy using a photosensi-tizer engineered for efficient two-photon excitation. They showed the selective closure of blood vessels in mice.