Association of Butyrylcholinesterase-K Allele and Apolipoprotein E epsilon 4 Allele with Cognitive Decline in Dementia with Lewy Bodies and Alzheimer's Disease

Vijayaraghavan Swetha; Darreh-Shori Taher; Rongve Arvid; Berge Guro; Sando Sigrid B.; White Linda R.; Auestad Bjorn H.; Witoelar Aree; Andreassen Ole A.; Ulstein Ingun D.; Aarsland Dag

首页> 外文期刊>Journal of Alzheimer's disease: JAD >Association of Butyrylcholinesterase-K Allele and Apolipoprotein E epsilon 4 Allele with Cognitive Decline in Dementia with Lewy Bodies and Alzheimer's Disease

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Association of Butyrylcholinesterase-K Allele and Apolipoprotein E epsilon 4 Allele with Cognitive Decline in Dementia with Lewy Bodies and Alzheimer's Disease

机译：丁酰基胆碱酯酶-K等位基因和载脂蛋白E epsilon 4等位基因，具有痴呆症的认知下降，具有Lewy体和阿尔茨海默病

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Background: A common polymorphism of the butyrylcholinesterase gene, the K-variant (BCHE-K) is associated with reduced butyrylcholinesterase (BuChE) activity. Insufficient studies exist regarding the frequency and role of BCHE-K in dementias.

机译：背景：k-变体（BCHE-K）的丁酰基胆碱酯酶基因的常见多态性与降低的丁酰胆碱酯酶（Buche）活性有关。存在关于BCHE-K在痴呆症中的频率和作用的研究不足。

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来源
《Journal of Alzheimer's disease: JAD》 |2016年第2期|共10页
作者
Vijayaraghavan Swetha; Darreh-Shori Taher; Rongve Arvid; Berge Guro; Sando Sigrid B.; White Linda R.; Auestad Bjorn H.; Witoelar Aree; Andreassen Ole A.; Ulstein Ingun D.; Aarsland Dag;
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作者单位

Karolinska Inst Dept Neurobiol Care Sci &

Soc Div Translat Alzheimer Neurobiol Ctr Alzheimer Res;

Karolinska Inst Dept Neurobiol Care Sci &

Soc Div Translat Alzheimer Neurobiol Ctr Alzheimer Res;

Haugesund Hosp Dept Res &

Innovat Haugesund Norway;

Norwegian Univ Sci &

Technol Fac Med Dept Neurosci N-7034 Trondheim Norway;

Norwegian Univ Sci &

Technol Fac Med Dept Neurosci N-7034 Trondheim Norway;

Norwegian Univ Sci &

Technol Fac Med Dept Neurosci N-7034 Trondheim Norway;

Univ Stavanger Dept Math &

Nat Sci Stavanger Norway;

Oslo Univ Hosp Div Mental Hlth &

Addict KG Jebsen Ctr Psychosis Res Oslo Norway;

Oslo Univ Hosp Div Mental Hlth &

Addict KG Jebsen Ctr Psychosis Res Oslo Norway;

Oslo Univ Hosp Norwegian Ctr Aging &

Hlth Dept Geriatr Med Oslo Norway;

Karolinska Inst Dept Neurobiol Care Sci &

Soc Div Translat Alzheimer Neurobiol Ctr Alzheimer Res;

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原文格式 PDF
正文语种 eng
中图分类神经病学与精神病学;
关键词
Apolipoprotein E genotype; butyrylcholinesterase-K; cognition; dementia; Mini-Mental State Examination;

机译：载脂蛋白E基因型;丁酰胆碱酯酶-K;认知;痴呆症;迷你精神状态考试;

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1. Association of Butyrylcholinesterase-K Allele and Apolipoprotein E epsilon 4 Allele with Cognitive Decline in Dementia with Lewy Bodies and Alzheimer's Disease [J] . Vijayaraghavan Swetha, Darreh-Shori Taher, Rongve Arvid, Journal of Alzheimer's disease: JAD . 2016,第2期

机译：丁酰胆碱酯酶-K等位基因和载脂蛋白E epsilon 4等位基因与路易体和阿尔茨海默氏病痴呆患者认知功能下降的关系
2. Apolipoprotein E (APOE) allele frequencies in late-onset sporadic Alzheimer's disease (AD), mixed dementia and vascular dementia: lack of association of epsilon 4 allele with AD in Italian octogenarian patients. [J] . Scacchi R, De Bernardini L, Mantuano E, Neuroscience Letters: An International Multidisciplinary Journal Devoted to the Rapid Publication of Basic Research in the Brain Sciences . 1995,第3期

机译：迟发性偶发性阿尔茨海默氏病（AD），混合性痴呆和血管性痴呆的载脂蛋白E（APOE）等位基因频率：意大利八岁患者中缺乏ε4等位基因与AD的关联。
3. BuChE-K and APOE epsilon4 allele frequencies in Lewy body dementias, and influence of genotype and hyperhomocysteinemia on cognitive decline. [J] . Lane R, He Y, Morris C, Movement disorders . 2009,第3期

机译：路易体痴呆中的BuChE-K和APOE epsilon4等位基因频率，以及基因型和高同型半胱氨酸血症对认知能力下降的影响。
4. Module differences of glucose metabolic brain network among Alzheimer’s disease, Parkinson’s disease dementia, Lewy body dementia and health control* [C] . Danyan Chen, Jiehui Jiang, Ping Wu, Annual International Conference of the IEEE Engineering in Medicine and Biology Society . 2018

机译：阿尔茨海默氏病，帕金森氏病痴呆症，路易体痴呆症和健康控制之间的葡萄糖代谢性大脑网络的模块差异*
5. Neural substrates of insulin-mediated memory facilitation in early Alzheimer's disease; the impact of the apolipoprotein E-epsilon-4 allele on hippocampal insulin responses [D] . Thomas, George P., Jr. 2009

机译：早期阿尔茨海默氏病中胰岛素介导的记忆促进作用的神经底物；载脂蛋白E-ε-4等位基因对海马胰岛素反应的影响
6. The Association Between Plasma α-Synuclein (α-syn) Protein Urinary Alzheimer-Associated Neuronal Thread Protein (AD7c-NTP) and Apolipoprotein Epsilon 4 (ApoE ɛ4) Alleles and Cognitive Decline in 60 Patients with Alzheimer’s Disease Compared with 28 Age-Matched Normal Individuals [O] . Shuang Lv, Xiao Zhou, Yiming Li, 2021

机译：血浆α-突触核蛋白（α-SYN）蛋白尿Alzheimer相关神经元蛋白（AD7C-NTP）和载脂蛋白ε4（ApoEɛ4）的等位基因和认知下降与28岁 - 匹配的正常人
7. Sex differences in the association of the apolipoprotein E epsilon 4 allele with incidence of dementia, cognitive impairment, and decline [O] . May A. Beydoun, Adel Boueiz, Marwan S. Abougergi, 2012

机译：脂脂蛋白Eε4等位基因的性差异，具有痴呆，认知障碍和下降的发生率

Association of Butyrylcholinesterase-K Allele and Apolipoprotein E epsilon 4 Allele with Cognitive Decline in Dementia with Lewy Bodies and Alzheimer's Disease

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