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首页> 外文期刊>AIChE Journal >Comparing true countercurrent and simulated moving-bed chromatographic reactors
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Comparing true countercurrent and simulated moving-bed chromatographic reactors

机译:比较真正的逆流和模拟移动床色谱反应器

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Simulated Moving Bed reactors (SMBR) combine chemical reaction and adsorptive separation within one single continuous and countercurrent unit. This integration promises substantial improvements inprocess performance,especially when applied to equilibrium-limited reactions involving such heat-sensitive products as fine chemicals and pharmaceuticals. In this work,the interplay among the relevant process design parameters is investigated. For this,an analytical solution of differential mass-balance equations for the corresponding true countercurrent process (TCC),using as a model system the reaction A-><-B+C with eachspecies exhibiting linear adsorption behavior,was developed.Based on this solution,criteria were derived for the optimum process design with respect to productivity and solvent consumption. Comparing these does not apply to SMBR units with a finite number of columns per section,that is,units of practical relevance,because the two units exhibit different residence time distrubtions and,hence,lead to different degrees of conversion.
机译:模拟移动床反应器(SMBR)在一个连续和逆流单元中将化学反应和吸附分离结合在一起。这种集成保证了工艺性能的显着提高,尤其是应用于涉及精细化学药品和药物等热敏产品的平衡受限反应时。在这项工作中,研究了相关工艺设计参数之间的相互作用。为此,使用模型A的反应A-> <-B + C表现出线性吸附行为,开发了相应真逆流过程(TCC)的微分质量平衡方程的解析解。针对生产率和溶剂消耗的最佳工艺设计,提出了解决方案,标准。比较这些不适用于每节具有有限列数(即实际相关单位)的SMBR单元,因为这两个单元表现出不同的停留时间偏差,因此导致不同的转化率。

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