Relation of plasma tryptophan concentrations during pregnancy to maternal sleep and mental well-being: The GUSTO cohort☆

摘要

Pregnantwomencommonlyreportsleepdiculties,whichisinpart due to the many physical and psychologic changes during pregnancy. A prevalence ranging between 50% and 80% has been reported for poor sleep quality or insomnia in pregnant women (Ko et al., 2012; Sivertsen et al., 2015). This prevalence is concerning because poor sleep quality has been associated with, gestational diabetes (Cai et al., 2017), ospring preterm birth, delays in childhood development (Facco et al., 2012; Zhou et al., 2016) and postnatal psychological distress (Tham et al., 2016).