Inhibiting EZH2 rescued bupivacaine-induced neuronal apoptosis in spinal cord dorsal root ganglia in mice

Zheng Jinwei; Chen Junping; Wu Guorong; Wu Chaoshuang; Wang Ruichun; Wang Wei

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Inhibiting EZH2 rescued bupivacaine-induced neuronal apoptosis in spinal cord dorsal root ganglia in mice

机译：抑制EZH2在小鼠中拯救了Bupivacaine诱导的神经元细胞凋亡

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摘要

In the present work, we intended to explore the function of enhancer of zeste homolog 2 (EZH2) in modulated anesthetic reagent bupivacaine-induced neuronal apoptosis in spinal cord dorsal root ganglia (DRG).

机译：在目前的工作中，我们打算探讨Zeste同源物2（EZH2）增强剂在脊髓背根神经节（DRG）中的调节麻醉剂试剂Bupivaine诱导的神经元细胞凋亡的功能。

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来源
《Journal of anesthesia》 |2018年第4期|共7页
作者
Zheng Jinwei; Chen Junping; Wu Guorong; Wu Chaoshuang; Wang Ruichun; Wang Wei;
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作者单位

Ningbo 2 Hosp Dept Anesthesiol 41 Northwest Rd Ningbo 315010 Zhejiang Peoples R China;

Ningbo 2 Hosp Dept Anesthesiol 41 Northwest Rd Ningbo 315010 Zhejiang Peoples R China;

Ningbo 2 Hosp Dept Anesthesiol 41 Northwest Rd Ningbo 315010 Zhejiang Peoples R China;

Ningbo 2 Hosp Dept Anesthesiol 41 Northwest Rd Ningbo 315010 Zhejiang Peoples R China;

Ningbo 2 Hosp Dept Anesthesiol 41 Northwest Rd Ningbo 315010 Zhejiang Peoples R China;

Ningbo 2 Hosp Dept Anesthesiol 41 Northwest Rd Ningbo 315010 Zhejiang Peoples R China;

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原文格式 PDF
正文语种 eng
中图分类外科学;
关键词
Spinal cord anesthesia; Dorsal root ganglion neuron; EZH2; Neurotoxicity;

机译：脊髓麻醉;背根神经节神经元;EZH2;神经毒性;

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专利

1. Inhibiting EZH2 rescued bupivacaine-induced neuronal apoptosis in spinal cord dorsal root ganglia in mice [J] . Zheng Jinwei, Chen Junping, Wu Guorong, Journal of anesthesia . 2018,第4期

机译：抑制EZH2在小鼠中拯救了Bupivacaine诱导的神经元细胞凋亡
2. Cancer pain and neuropathic pain are associated with A β sensory neuronal plasticity in dorsal root ganglia and abnormal sprouting in lumbar spinal cord [J] . Yong Fang Zhu, Jacek M Kwiecien, Wojciech Dabrowski, Molecular pain . 2018,第14期

机译：癌症疼痛和神经性疼痛与背根神经节中的Aβ感觉神经元可塑性和腰脊髓异常发芽有关
3. Neuronal nitric oxide synthase (nNOS) mRNA is down-regulated, and constitutive NOS enzymatic activity decreased, in thoracic dorsal root ganglia and spinal cord of the rat by a substance P N-terminal metabolite. [J] . Kovacs KJ, Cai Y, Larson AA The European Journal of Neuroscience . 2001,第4期

机译：在大鼠的胸背根神经节和脊髓中，神经质一氧化氮合酶（nNOS）mRNA下调，组成型NOS酶活性降低。
4. DORSAL ROOT IMPLANT ON LESIONED SPINAL CORD MORPHOLOGIC FINDINGS OF REGENERATION OF SYNAPSES IN THE MAMMALIAN SPINAL CORD-REPAIR AND RECOVERY [C] . C. C. Turbes Annual Rocky Mountain Bioengineering Symposium . 2003

机译：哺乳动物脊髓修复和恢复突变脊髓形态学发现的背根植入物
5. GABAB receptor expression, function, and trafficking in the dorsal horn of the spinal cord and dorsal root ganglia. [D] . Engle, Mitchell Philip. 2007

机译：GABA B受体在脊髓背角和背根神经节中的表达，功能和运输。
6. Cancer pain and neuropathic pain are associated with Aβ sensory neuronal plasticity in dorsal root ganglia and abnormal sprouting in lumbar spinal cord [O] . Yong Fang Zhu, Jacek M Kwiecien, Wojciech Dabrowski, 2018

机译：癌痛和神经性疼痛与背根神经节的Aβ感觉神经元可塑性和腰脊髓异常发芽有关
7. The changes of nociception and the signal molecules expression in the dorsal root ganglia and the spinal cord after cold water swimming stress in mice [O] . Jing-Hui Feng, Su-Min Sim, Jung-Seok Park, 2021

机译：小鼠冷水游泳胁迫后背根神经节与脊髓中伤害伤害和信号分子表达的变化

Inhibiting EZH2 rescued bupivacaine-induced neuronal apoptosis in spinal cord dorsal root ganglia in mice

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