Rigorous Trial Design Is Essential to Understand the Role of Opioid Receptors in Ketamine's Antidepressant Effect Reply

Krystal John H.; Yoon Gihyun; Petrakis Ismene L.

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Rigorous Trial Design Is Essential to Understand the Role of Opioid Receptors in Ketamine's Antidepressant Effect Reply

机译：严格的试验设计对于了解阿片受体在氯胺酮的抗抑郁效应答复中的作用至关重要

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《JAMA psychiatry》 |2019年第6期|共2页
作者
Krystal John H.; Yoon Gihyun; Petrakis Ismene L.;
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作者单位

Yale Univ Sch Med Dept Psychiat Vet Affairs Connecticut Healthcare Syst New Haven CT USA;

Yale Univ Sch Med Dept Psychiat Vet Affairs Connecticut Healthcare Syst New Haven CT USA;

Yale Univ Sch Med Dept Psychiat Vet Affairs Connecticut Healthcare Syst New Haven CT USA;

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正文语种 eng
中图分类神经病学与精神病学;
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1. Rigorous Trial Design Is Essential to Understand the Role of Opioid Receptors in Ketamine's Antidepressant Effect Reply [J] . Krystal John H., Yoon Gihyun, Petrakis Ismene L. JAMA psychiatry . 2019,第6期

机译：严格的试验设计对于了解阿片受体在氯胺酮的抗抑郁效应答复中的作用至关重要
2. Essential roles of neuropeptide VGF regulated TrkB/mTOR/BICC1 signaling and phosphorylation of AMPA receptor subunit GluA1 in the rapid antidepressant-like actions of ketamine in mice [J] . Mengxin Shen, Dan Lv, Xu Liu, Brain research bulletin . 2018,第期

机译：神经肽VGF调节TRKB / mTOR / BICC1信号传导和磷酸化AMPA受体亚单位GLUA1在小鼠中的快速抗抑郁作用中的信号和磷酸化
3. Essential roles of AMPA receptor GluAl phosphorylation and presynaptic HCN channels in fast-acting antidepressant responses of ketamine [J] . Ke Zhang, Ting Xu, Zhongmin Yuan, Science Signaling . 2016,第458期

机译：AMPA受体GluA1磷酸化和突触前HCN通道在氯胺酮快速抗抑郁反应中的重要作用
4. Opioid Ligand Binding to Opioid Receptors: Insight and Implications for Peptide Design [C] . Michael J. Ferracane, Jane V. Aldrich American Peptide Symposium . 2015

机译：阿片类配体与阿片受体的结合：肽设计的见解和影响
5. Cellular, Synaptic, and Circuit-Level Roles for GluN2B-Containing NMDA Receptors in the Antidepressant Effect of Ketamine [D] . Miller, Oliver Helms 2016

机译：含GluN2B的NMDA受体在氯胺酮抗抑郁作用中的细胞，突触和电路水平作用
6. Essential roles of AMPA receptor GluA1 phosphorylation and presynaptic HCN channels in fast-acting antidepressant responses of ketamine [O] . Ke Zhang, Ting Xu, Zhongmin Yuan, -1

机译：AMPA受体GluA1磷酸化和突触前HCN通道在氯胺酮快速抗抑郁反应中的重要作用
7. Attenuation of Antidepressant Effects of Ketamine by Opioid Receptor Antagonism: Is It a Ketamine-Specific Effect? [O] . Revital Amiaz 2019

机译：阿片受体拮抗作用的氯胺酮抗抑郁作用的衰减：是氯胺酮特异性效果吗？
8. Novel Approach for Effectively Treating SCI Pain, Improving Opioid Efficacy, and Preventing Opioid Induced Constipation: Key Role of Toll-Like Receptor 4 (TLR4). [R] . Watkins, L. 2016

机译：有效治疗sCI疼痛，提高阿片类药物功效，预防阿片类药物引起的便秘的新方法：Toll样受体4（TLR4）的关键作用。

Rigorous Trial Design Is Essential to Understand the Role of Opioid Receptors in Ketamine's Antidepressant Effect Reply

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