BRONSTED ACID-PROMOTED MULTICOMPONENT REACTION FOR THE CONSTRUCTION OF PYRROLOCOUMARIN DERIVATIVES

摘要

An efficient one-pot synthesis of functionalized indole-containing pyrrolocoumarin derivatives via a three-component reaction of 4-aminocoumarins, arylglyoxal monohydrates and indoles promoted by p-TSA in ethanol is described. The attractive features of this protocol are simple starting materials, operational simplicity, short reaction time and moderate to good yields.