A CONVENIENT AND FACLLE SYNTHESIS OF 3-TRIFLUOROMETHYL-1,2,5-OXADIAZOLES WITH THE USE OF SILICA GEL AS AN EFFECTIVE CATALYST

摘要

Silica gel catalyzed intramolecular dehydration of 1,1,1-trifluoro-alkane-2,3-dione dioximes (2)afforded 3-trifluoromethyl-1,2,5-oxadiazoles(3) in satisfactory yields.