CONFORMATIONAL CONTROL OF A PYRROLE-BASED AMIDE PENTAMER BY DIHYDROGEN PHOSPHATE ANION BINDING

摘要

Conformational control is of importance for compounds to implement their properties and functions. In this work, a pyrrole-based amide pentamer 1 was synthesized. NOESY NMR experiments show it adopts two main conformations, one of which can be sorted out and stabilized via binding of a dihydrogen phosphate anion.