Association of Ticagrelor vs Clopidogrel With Major Adverse Coronary Events in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention

摘要

Question What is the association between ticagrelor vs clopidogrel and major adverse coronary events, major bleeding, and dyspnea in patients with acute coronary syndrome treated with percutaneous coronary intervention? Findings In this cohort study of 11 & x202f;185 patients, ticagrelor was not associated with a statistically significantly lower risk of major adverse coronary events compared with clopidogrel. However, it was associated with statistically significantly more major bleeding and dyspnea. Meaning Ticagrelor was not associated with a lower risk of major adverse coronary events in patients with acute coronary syndrome who underwent percutaneous coronary intervention.