C679X loss-of-function PCSK9 variant lowers fasting glucose levels in a black South African population: A longitudinal study

Chikowore Tinashe; Cockeran Marike; Conradie Karin R.; van Zyl Tertia

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C679X loss-of-function PCSK9 variant lowers fasting glucose levels in a black South African population: A longitudinal study

机译：C679X失去功能损失PCSK9变体降低了黑色南非人口中的空腹葡萄糖水平：纵向研究

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Aims: To determine the longitudinal association of the loss-of-function (LOF) PCSK9 variants (C679X and A443T), proxies of PCSK9 inhibitor drugs, with LDL-C, fasting glucose and glycated hemoglobin.

机译：目的：确定函数丧失（LOF）PCSK9变体（C679X和A443T）的纵向关联，PCSK9抑制剂药物的代理，用LDL-C，空腹葡萄糖和糖化血红蛋白。

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来源
《Diabetes research and clinical practice》 |2018年第2018期|共7页
作者
Chikowore Tinashe; Cockeran Marike; Conradie Karin R.; van Zyl Tertia;
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作者单位

Univ Witwatersrand MRC Wits Dev Pathways Hlth Res Unit Dept Pediat Fac Hlth Sci Johannesburg;

North West Univ Sch Math &

Stat Sci ZA-2520 Potchefstroom North West Prov South Africa;

North West Univ Ctr Excellence Nutr ZA-2520 Potchefstroom North West Prov South Africa;

North West Univ Ctr Excellence Nutr ZA-2520 Potchefstroom North West Prov South Africa;

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原文格式 PDF
正文语种 eng
中图分类内分泌腺疾病及代谢病;
关键词
PCSK9; Type 2 diabetes; LDL-C; Loss of function; A443T; C679X; Black South African population;

机译：PCSK9;2型糖尿病;LDL-C;失去功能;A443T;C679x;黑南非人口;

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1. C679X loss-of-function PCSK9 variant lowers fasting glucose levels in a black South African population: A longitudinal study [J] . Chikowore Tinashe, Cockeran Marike, Conradie Karin R., Diabetes research and clinical practice . 2018,第期

机译：C679X失去功能损失PCSK9变体降低了黑色南非人口中的空腹葡萄糖水平：纵向研究
2. C679X loss-of-function PCSK9 variant is associated with lower fasting glucose in black South African adolescents: Birth to Twenty Plus Cohort [J] . Tinashe Chikowore, Venesa Sahibdeen, Liesl M. Hendry, Journal of Clinical & Translational Endocrinology . 2019,第1期

机译：C679X功能丧失 PCSK9 变异与南非黑人青少年的空腹血糖降低有关：出生于二十多岁队列
3. Nutrient Patterns Associated with Fasting Glucose and Glycated Haemoglobin Levels in a Black South African Population [J] . Tinashe Chikowore, Pedro T. Pisa, Tertia van Zyl, Nutrients . 2017,第1期

机译：南非黑人人群中与空腹血糖和糖化血红蛋白水平相关的营养模式
4. The need to prepare more South African black scholars for engineering studies [C] . Beute, N. . 1997

机译：需要准备更多南非黑人学者进行工程研究
5. Low Glycemic Index Diet and Aerobic Activities Lowers Fasting Blood Glucose Levels [D] . Morgan, Cheryl. 2018

机译：低血糖指数饮食和有氧活动降低了空腹血糖水平
6. C679X loss-of-function PCSK9 variant is associated with lower fasting glucose in black South African adolescents: Birth to Twenty Plus Cohort [O] . Tinashe Chikowore, Venesa Sahibdeen, Liesl M. Hendry, 2019

机译：C679X功能丧失的PCSK9变体与南非黑人青少年的空腹血糖降低有关：二十多岁队列的出生
7. Nutrient Patterns Associated with Fasting Glucose and Glycated Haemoglobin Levels in a Black South African Population [O] . Tinashe Chikowore, Pedro T. Pisa, Tertia van Zyl, 2017

机译：南非黑人人群中与空腹葡萄糖和糖化血红蛋白水平相关的营养模式

C679X loss-of-function PCSK9 variant lowers fasting glucose levels in a black South African population: A longitudinal study

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