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Pathways from parental mental disorders to offspring's work disability due to depressive or anxiety disorders in early adulthood—The 1987 Finnish Birth Cohort

机译：父母精神障碍到后代的后期工作障碍因成年早期的抑郁或焦虑症 - 1987年芬兰出生队列

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Background >Parental mental disorders have been shown to predict offspring's mental health problems. We examined whether pathways from parental mental disorders to offspring's psychiatric work disability in early adulthood are mediated through offspring's mental disorders and social disadvantage in adolescence. </section> <section xml:id="da22847-sec-0020"> <title type="main">Methods >Study population consisted of the 1987 Finnish Birth Cohort. Data on parents’ psychiatric care or work disability due to mental diagnosis between 1987 and 2000 and the cohort participants’ health and social factors between 2001 and 2005 were derived from administrative national registers. From 2006 through 2015, 52,182 cohort participants were followed for admittance of psychiatric work disability due to depressive or anxiety disorders. First, we applied a pathway analysis to examine the occurrence of each path. We then used mediation analysis to assess the proportion of association between parental mental disorders and work disability mediated by offspring's health and social disadvantage. </section> <section xml:id="da22847-sec-0030"> <title type="main">Results >The pathway model indicated that the association from parental mental disorders to offspring's work disability due to depressive or anxiety disorder is through mental disorders and social disadvantage in adolescence. Odds Ratio for the total effect of parental mental disorders on offspring's psychiatric work disability was 1.85 (95% confidence interval [CI] 1.46–2.34) in the model including offspring's mental disorders that mediated this association by 35%. Corresponding results were 1.86 (95% CI 1.47–2.35) and 28% for social disadvantage in adolescence. </section> <section xml:id="da2284 </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> <div class="translation abstracttxt"> <span class="zhankaihshouqi fivelineshidden" id="abstract"> <span>机译：</span><abstract type =“main”xml：lang =“en”> <section xml：id =“da22847-sec-0010”> <标题类型=“main”>背景</ title> >父母精神障碍显示预测后代的心理健康问题。我们研究了在成年早期从成年早期对后代精神病工作残疾的父母精神障碍的途径是通过后代的精神障碍和青春期的社会劣势介导的。</ p> </ section> <section XML：ID =“DA22847-SEC-0020”> <标题类型=“main”>方法</ title> >学习人口包括1987年芬兰出生队列。 1987年至2000年期间的精神诊断和2001年至2005年期间的精神诊断导致的父母精神病护理或工作障碍的数据来自行政国家登记册。从2006年到2015年，由于抑郁或焦虑症，52,182个队列参与者被接受入境精神病工作残疾。首先，我们应用了途径分析以检查每个路径的发生。然后，我们使用中介分析来评估后代健康和社会劣势介导的父母精神障碍和工作残疾之间关联的比例。</ p> </ section> <section XML：ID =“da22847-sec-0030”> <标题类型=“main”>结果</ title> >途径模型表明，由于抑郁或焦虑症导致的父母精神障碍与后代的工作障碍是通过心灵的精神障碍和社会劣势。父母精神障碍对后代精神病工作残疾的总效果的差额比为1.85（95％的置信区间[CI] 1.46-2.34），包括后代的精神障碍，将此协会介导35％。相应的结果为1.86（95％CI 1.47-2.35）和青春期社会劣势的28％。</ p> </ section> <section XML：ID =“DA2284 </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> </div> <div class="record"> <h2 class="all_title" id="enpatent33" >著录项</h2> <ul> <li> <span class="lefttit">来源</span> <div style="width: 86%;vertical-align: text-top;display: inline-block;"> <a href='/journal-foreign-32884/'>《Depression and anxiety》</a> <b style="margin: 0 2px;">|</b><span>2019年第4期</span><b style="margin: 0 2px;">|</b><span>共8页</span> </div> </li> <li> <div class="author"> <span class="lefttit">作者</span> <p id="fAuthorthree" class="threelineshidden zhankaihshouqi"> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Halonen Jaana I.&option=202" target="_blank" rel="nofollow">Halonen Jaana I.;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Merikukka Marko&option=202" target="_blank" rel="nofollow">Merikukka Marko;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Gissler Mika&option=202" target="_blank" rel="nofollow">Gissler Mika;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Kerkel? Martta&option=202" target="_blank" rel="nofollow">Kerkel? Martta;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Virtanen Marianna&option=202" target="_blank" rel="nofollow">Virtanen Marianna;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Ristikari Tiina&option=202" target="_blank" rel="nofollow">Ristikari Tiina;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Hiilamo Heikki&option=202" target="_blank" rel="nofollow">Hiilamo Heikki;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Lallukka Tea&option=202" target="_blank" rel="nofollow">Lallukka Tea;</a> </p> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zkzz" style="display: none;">展开▼</span> </div> </li> <li> <div style="display: flex;"> <span class="lefttit">作者单位</span> <div style="position: relative;margin-left: 3px;max-width: 639px;"> <div class="threelineshidden zhankaihshouqi" id="fOrgthree"> <p>Finnish Institute of Occupational HealthHelsinki Finland;</p> <p>Department of WelfareNational Institute for Health and Welfare (THL)Oulu Finland;</p> <p>Information Services DepartmentNational Institute for Health and Welfare (THL)Helsinki Finland;</p> <p>Department of WelfareNational Institute for Health and Welfare (THL)Oulu Finland;</p> <p>Department of Public Health and Caring SciencesUniversity of UppsalaUppsala Sweden;</p> <p>Department of WelfareNational Institute for Health and Welfare (THL)Oulu Finland;</p> <p>Social and Public Policy Department of Social ResearchUniversity of HelsinkiHelsinki Finland;</p> <p>Finnish Institute of Occupational HealthHelsinki Finland;</p> </div> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zhdw" style="display: none;">展开▼</span> </div> </div> </li> <li > <span class="lefttit">收录信息</span> <span style="width: 86%;vertical-align: text-top;display: inline-block;"></span> </li> <li> <span class="lefttit">原文格式</span> <span>PDF</span> </li> <li> <span class="lefttit">正文语种</span> <span>eng</span> </li> <li> <span class="lefttit">中图分类</span> <span>R749.72; </span> </li> <li class="antistop"> <span class="lefttit">关键词</span> <p style="width: 86%;vertical-align: text-top;"> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=anxiety&option=203" rel="nofollow">anxiety;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=child/adolescent&option=203" rel="nofollow">child/adolescent;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=depression&option=203" rel="nofollow">depression;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=epidemiology&option=203" rel="nofollow">epidemiology;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=family&option=203" rel="nofollow">family;</a> </p> <div class="translation"> 机译：焦虑;儿童/青少年;抑郁;流行病学;家庭; </div> </li> </ul> </div> </div> <div class="literature cardcommon"> <div class="similarity "> <h3 class="all_title" id="enpatent66">相似文献</h3> <div class="similaritytab clearfix"> <ul> <li class="active" >外文文献</li> <li >中文文献</li> <li >专利</li> </ul> </div> <div class="similarity_details"> <ul > <li> <div> <b>1. </b><a class="enjiyixqcontent" href="/journal-foreign-detail/0704025195366.html">Pathways from parental mental disorders to offspring's work disability due to depressive or anxiety disorders in early adulthood—The 1987 Finnish Birth Cohort</a> <b>[J]</b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Halonen Jaana I.&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Halonen Jaana I.,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Merikukka Marko&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Merikukka Marko,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Gissler Mika&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Gissler Mika,</a> <a href="/journal-foreign-32884/" target="_blank" rel="nofollow" class="tuijian_authcolor">Depression and anxiety .</a> <span>2019</span><span>,第4期</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：父母精神障碍到后代的后期工作障碍因成年早期的抑郁或焦虑症 - 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href="/academic-journal-cn_chinese-journal-clinicians-electronic-edition_thesis/0201228437382.html">成年早期抑郁患者自我同一性与父母教养方式的关系研究</a> <b>[J]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=何兴鑫&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 何兴鑫</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=宋丽萍&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,宋丽萍</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=白雪姣&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,白雪姣</a> <span> <a href="/journal-cn-5909/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 中华临床医师杂志（电子版） </a> </span> <span> . 2017</span><span>,第006期</span> </span> </div> </li> <li> <div> <b>5. </b><a class="enjiyixqcontent" href="/academic-journal-cn_chinese-journal-rural-medicine-pharmacy_thesis/0201253477189.html">生命早期应激诱发成年后精神障碍的临床研究进展</a> <b>[J]</b> <span> <a 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class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：根据SHEVCHENKO-BITENSKYI K.V.对患有精神疾病的患者进行的焦虑，抑郁症和去个性化的鉴别诊断方法 </span> </p> </li> <li> <div> <b>4. </b><a class="enjiyixqcontent" href="/patent-detail/06130424522813.html">MENTAL ILLNESS RECOGNITION METHOD USING AN N100 AMPLITUDE SLOPE CAPABLE OF PRECISELY RECOGNIZING A UNIPOLAR DEPRESSIVE DISORDER AND BIPOLAR DEPRESSIVE DISORDER</a> <b>[P]</b> . <span> 外国专利：  KR20110096394A </span> <span> . 2011-08-30</span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：使用能够精确识别单眼抑郁症和双极抑郁症的N100振幅斜率的心理疾病识别方法 </span> </p> </li> <li> <div> <b>5. </b><a class="enjiyixqcontent" href="/patent-detail/06130409480507.html">compound of formula (i), or a salt thereof; composition of witania somnifera (ws) extract; pharmaceutical or nutraceutical composition; method of producing a composition of witania somnifera (ws) extract; method of producing a compound of formula (i); method of treating or preventing a dementia-related disorder in an individual; and method of treating or preventing an anxiety disorder or a depressive disorder in an individual</a> <b>[P]</b> . <span> 外国专利：  BR112014010868A8 </span> <span> . 2017-06-20</span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：式（i）的化合物或其盐;茄子提取物的成分;药物或营养保健品组合物;一种用于生产茄子的提取物的方法。制备式（i）化合物的方法;治疗或预防个体与痴呆症相关的疾病的方法;或治疗个体的焦虑症或抑郁症的方法和方法 </span> </p> </li> </ul> </div> </div> </div> <div class="theme cardcommon" style="overflow: auto;display:none"> <h3 class="all_title" id="enpatent55">相关主题</h3> <ul id="subject"> </ul> </div> </div> </div> </div> <div class="right rightcon"> <div class="details_img cardcommon clearfix" style="margin-bottom: 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