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Phenotypic analysis of monocytes and CD4(+) T cells in hepatitis E patients with or without pregnancy

机译:乙型肝炎患者单核细胞和CD4(+)T细胞的表型分析或妊娠期患者的表型分析

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摘要

High mortality in pregnant women is a characteristic of hepatitis E virus (HEV) infection. Role of monocytes/T cells in HEV infection during pregnancy is still unclear. We compared CD14(+) monocytes and CD4(+)T cells by flow-cytometry in hepatitis-E patients including 13 pregnant (Antenatal care, ANC), 25 non-ANC patients and respective controls (12 and 20). Non-ANC-patients showed significantly higher frequency of monocytes with increased expression of CD80, CD86 and HLA-DR than control individuals (p < 0.001).
机译:孕妇的高死亡率是乙型肝炎病毒(HEV)感染的特征。 单核细胞/ T细胞在怀孕期间HEV感染的作用仍不清楚。 我们将CD14(+)单核细胞和CD4(+)T细胞与乙型肝炎患者的流式细胞术进行比较,包括13例怀孕(产前护理,ANC),25例非ANC患者和各自对照(12和20)。 非ANC患者显示出明显较高的单核细胞频率,随着CD80,CD86和HLA-DR的增加而不是对照个体(P <0.001)。

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