The preS deletion of hepatitis B virus (HBV) is associated with liver fibrosis progression in patients with chronic HBV infection

Li Fan; Li Xiaodong; Yan Tao; Liu Yan; Cheng Yongqian; Xu Zhihui; Shao Qing; Liao Hao; Huang Pengyu; Li Jin; Chen Guo-Feng; Xu Dongping

首页> 外文期刊>Hepatology international >The preS deletion of hepatitis B virus (HBV) is associated with liver fibrosis progression in patients with chronic HBV infection

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The preS deletion of hepatitis B virus (HBV) is associated with liver fibrosis progression in patients with chronic HBV infection

机译：乙型肝炎病毒（HBV）的PRES缺失与慢性HBV感染患者的肝纤维化进展相关

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Background and aims Limited data are available regarding the association of hepatitis B virus (HBV) mutations with liver fibrosis in HBV infection. The study aimed to clarify whether HBV preS deletion mutation is associated with liver fibrosis progression.

机译：背景和AIMS有限的数据对于HBV感染中具有肝纤维化的乙型肝炎病毒（HBV）突变的关联提供的数据。该研究旨在阐明HBV Pres缺失突变是否与肝纤维化进展相关。

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来源
《Hepatology international》 |2018年第2期|共11页
作者
Li Fan; Li Xiaodong; Yan Tao; Liu Yan; Cheng Yongqian; Xu Zhihui; Shao Qing; Liao Hao; Huang Pengyu; Li Jin; Chen Guo-Feng; Xu Dongping;
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作者单位

Beijing 302 Hosp Liver Cirrhosis Diag &

Treatment Ctr 2 100 Middle St 4th Ring Rd Beijing 100039;

Beijing 302 Hosp Inst Infect Dis Res Ctr Clin &

Translat Med 100 Middle St 4th Ring Rd Beijing;

Beijing 302 Hosp Int Liver Dis Diag &

Treatment Ctr Beijing 100039 Peoples R China;

Beijing 302 Hosp Res Ctr Clin &

Translat Med Beijing 100039 Peoples R China;

Beijing 302 Hosp Int Liver Dis Diag &

Treatment Ctr Beijing 100039 Peoples R China;

Beijing 302 Hosp Inst Infect Dis Res Ctr Clin &

Translat Med 100 Middle St 4th Ring Rd Beijing;

Beijing 302 Hosp Liver Cirrhosis Diag &

Treatment Ctr 2 100 Middle St 4th Ring Rd Beijing 100039;

Beijing 302 Hosp Inst Infect Dis Res Ctr Clin &

Translat Med 100 Middle St 4th Ring Rd Beijing;

Beijing 302 Hosp Inst Infect Dis Res Ctr Clin &

Translat Med 100 Middle St 4th Ring Rd Beijing;

Beijing 302 Hosp Inst Infect Dis Res Ctr Clin &

Translat Med 100 Middle St 4th Ring Rd Beijing;

Beijing 302 Hosp Liver Cirrhosis Diag &

Treatment Ctr 2 100 Middle St 4th Ring Rd Beijing 100039;

Beijing 302 Hosp Inst Infect Dis Res Ctr Clin &

Translat Med 100 Middle St 4th Ring Rd Beijing;

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原文格式 PDF
正文语种 eng
中图分类消化系及腹部疾病;
关键词
Hepatitis B virus; preS deletion; Liver fibrosis; Covalently closed circular DNA;

机译：乙型肝炎病毒;PRES删除;肝纤维化;共价封闭的圆形DNA;

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专利

1. The preS deletion of hepatitis B virus (HBV) is associated with liver fibrosis progression in patients with chronic HBV infection [J] . Li Fan, Li Xiaodong, Yan Tao, Hepatology international . 2018,第2期

机译：乙型肝炎病毒（HBV）的PRES缺失与慢性HBV感染患者的肝纤维化进展相关
2. PreS deletion profiles of hepatitis B virus (HBV) are associated with clinical presentations of chronic HBV infection [J] . Li Xiaodong, Qin Yaqun, Liu Yan, Journal of clinical virology: The official publication of the Pan American Society for Clinical Virology . 2016,第Null期

机译：乙型肝炎病毒（HBV）的PreS缺失谱与慢性HBV感染的临床表现有关
3. PreS deletion profiles of hepatitis B virus (HBV) are associated with clinical presentations of chronic HBV infection [J] . Li Xiaodong, Qin Yaqun, Liu Yan, Journal of clinical virology: The official publication of the Pan American Society for Clinical Virology . 2016,第Null期

机译：乙型肝炎病毒（HBV）的Pres缺失谱与慢性HBV感染的临床介绍相关
4. Proteomic investigation of the mechanism of infection of Hepatitis B virus (HBV) in HepaRG cells [C] . Catalina Petrareanu, Izabela Sokolowska, Alina Macovei, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2013

机译：肝炎病毒（HBV）在肝炎细胞中感染机制的蛋白质组学研究
5. Pathogenesis of hepatitis B virus infection: The effect of the HBx protein from HBV on cell survival and death. [D] . Diao, Jingyu. 2002

机译：乙型肝炎病毒感染的发病机制：HBV中的HBx蛋白对细胞存活和死亡的影响。
6. rt269I Type of Hepatitis B Virus (HBV) Leads to HBV e Antigen Negative Infections and Liver Disease Progression via Mitochondrial Stress Mediated Type I Interferon Production in Chronic Patients With Genotype C Infections [O] . So-Young Lee, Yu-Min Choi, Song-Ji Oh, -1

机译：rt269I型乙型肝炎病毒（HBV）通过线粒体应激介导的慢性C型基因感染患者产生HBV e抗原阴性感染和肝病进展。
7. Liver fibrosis regression and progression during controlled hepatitis B virus infection among HIV–HBV patients treated with tenofovir disoproxil fumarate in France: a prospective cohort study [O] . Anders Boyd, Julie Bottero, Patrick Miailhes, 2017

机译：在法国使用替诺福韦地索普西富马酸盐治疗的HIV-HBV患者中控制乙型肝炎病毒感染期间肝纤维化的消退和进展：一项前瞻性队列研究

The preS deletion of hepatitis B virus (HBV) is associated with liver fibrosis progression in patients with chronic HBV infection

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