TRIP-A Powerful Bronsted Acid Catalyst for Asymmetric Synthesis

摘要

Asymmetric organocatalysis has become one of the most active areas of research in chemistry since the beginning of this century.In particular,the last five years have witnessed an enormous growth in terms of new catalyst design and reaction development and,most importantly,several new catalytic concepts have emerged.Asymmetric Bronsted acid catalysis is one of the newly developed organocatalytic concepts that has had a substantial impact on this area.This type of catalysis can be subdivided into two classes,general acid catalysis and specific acid catalysis.