Proactive maintenance therapy of canine atopic dermatitis with the anti‐        fc >IL/fc>IL        ‐31 lokivetmab. Can a monoclonal antibody blocking a single cytokine prevent allergy flares?

Tamamoto‐Mochizuki Chie; Paps Judy S.; Olivry Thierry

首页> 外文期刊>Veterinary Dermatology >Proactive maintenance therapy of canine atopic dermatitis with the anti‐ fc >IL/fc>IL ‐31 lokivetmab. Can a monoclonal antibody blocking a single cytokine prevent allergy flares?

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Proactive maintenance therapy of canine atopic dermatitis with the anti‐ fc >IL/fc>IL ‐31 lokivetmab. Can a monoclonal antibody blocking a single cytokine prevent allergy flares?

机译：犬类疗法治疗犬特应疗法具有抗-LT;型FC> IL> IL -31 Lokivetmab。可以阻断单克隆抗体是否阻止单个细胞因子防止过敏耀斑？

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来源
《Veterinary Dermatology》 |2019年第2期|共9页
作者
Tamamoto‐Mochizuki Chie; Paps Judy S.; Olivry Thierry;
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Department of Clinical SciencesNC State University1060 William Moore Drive Raleigh NC 27607 USA;

Department of Clinical SciencesNC State University1060 William Moore Drive Raleigh NC 27607 USA;

Department of Clinical SciencesNC State University1060 William Moore Drive Raleigh NC 27607 USA;

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正文语种 eng
中图分类皮肤病;
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1. Proactive maintenance therapy of canine atopic dermatitis with the anti‐ fc >IL/fc>IL ‐31 lokivetmab. Can a monoclonal antibody blocking a single cytokine prevent allergy flares? [J] . Tamamoto‐Mochizuki Chie, Paps Judy S., Olivry Thierry Veterinary Dermatology . 2019,第2期

机译：犬类疗法治疗犬特应疗法具有抗-LT;型FC> IL> IL -31 Lokivetmab。可以阻断单克隆抗体是否阻止单个细胞因子防止过敏耀斑？
2. A blinded, randomized, placebo-controlled trial of the safety of lokivetmab (ZTS-00103289), a caninized anti-canine IL-31 monoclonal antibody in client-owned dogs with atopic dermatitis [J] . Michels Gina M., Walsh Kelly F., Kryda Kristina A., Veterinary Dermatology . 2016,第6期

机译：Lokivetmab（ZTS-00103289）（一种犬化的抗犬IL-31单克隆抗体）在特应性皮炎客户养狗中的安全性的盲目的，随机，安慰剂对照试验
3. A blinded, randomized, placebo-controlled, dose determination trial of lokivetmab (ZTS-00103289), a caninized, anti-canine IL-31 monoclonal antibody in client owned dogs with atopic dermatitis [J] . Michels Gina M., Ramsey Deborah S., Walsh Kelly F., Veterinary Dermatology . 2016,第6期

机译：Lokivetmab（ZTS-00103289）（一种犬化的抗犬IL-31单克隆抗体）在患有特应性皮炎的客户拥有的狗中的盲，随机，安慰剂对照剂量确定试验
4. Defining the Role of Fc-Fc Gamma Receptor Interactions in the Anti-Tumor Function of Anti-CD137 Monoclonal Antibody Therapy. [D] . Sallin, MIchelle. 2013

机译：定义Fc-Fcγ受体相互作用在抗CD137单克隆抗体治疗的抗肿瘤功能中的作用。
5. Effects of anti-IL-4 receptor monoclonal antibody on in vitro T cell cytokine levels: IL-4 production by T cells from non-atopic donors [O] . D M A Bullens, A Kasran, X Peng, 1998

机译：抗IL-4受体单克隆抗体对体外T细胞细胞因子水平的影响：非特应性供体的T细胞产生IL-4
6. P4940Infarct size in a rat model of STEMI is reduced by interleukin-6 trans-signalling blockade using sgp130fc but not an anti-IL6R monoclonal antibody [O] . M. George, D. Stuckey, V. Taylor, 2017

机译：使用SGP130FC的白细胞介素-6反式信号阻断，但不是抗IL6R单克隆抗体的Inter介素-6反式信号传导阻断，降低了茎的大鼠Stemi模型中的p4940.infarct大小

Proactive maintenance therapy of canine atopic dermatitis with the anti‐ fc >IL/fc>IL ‐31 lokivetmab. Can a monoclonal antibody blocking a single cytokine prevent allergy flares?

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