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Predicting pharmacokinetic profile of therapeutic antibodies after iv injection from only the data after sc injection in cynomolgus monkey

机译:在Cynomolgus猴子中仅从SC注射后预测IV注射后的治疗抗体的药代动力学曲线

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摘要

1. The number of developed therapeutic monoclonal antibodies (mAbs) has increased in this decade. This study aims to predict their pharmacokinetic profiles after intravenous (iv) injection using only the data taken after subcutaneous (sc) injection in cynomolgus monkey.
机译:1.发育的治疗性单克隆抗体(MAB)的数量在这十年内增加。 本研究旨在仅使用皮下(SC)注射术中的静脉内(IV)注射后预测其药代动力学谱。

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