Effect of Asiatic Acid on the Treatment of Spinal Cord Injury: An Experimental Study in Rats

Gurcan Oktay; Gurcat Ahmet Gurhan; Kazanci Atilla; Senturk Salim; Bodur Ebru; Karaca Ebru Umay; Turkoglu Omer Faruk; Bavbek Murad

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Effect of Asiatic Acid on the Treatment of Spinal Cord Injury: An Experimental Study in Rats

机译：亚洲酸对脊髓损伤治疗的影响：大鼠实验研究

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AIM: Spinal cord injury (SCI) is a devastating condition of the central nervous system. There is no proven therapeutic agent for the treatment of this complex disorder. Asiatic acid (AA) has been used as an anti-inflammatory and anti-oxidant agent in Eastern countries for many years. The aim of this study was to investigate the effectiveness of AA on the treatment of traumatic SCI in rats.

机译：目的：脊髓损伤（SCI）是中枢神经系统的毁灭性条件。没有经过验证的治疗剂治疗这种复杂疾病。多年来已被用作东部国家的抗炎和抗氧化剂的亚洲酸（AA）。本研究的目的是探讨AA对大鼠创伤性SCI治疗的有效性。

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来源
《Turkish neurosurgery》 |2017年第2期|共6页
作者
Gurcan Oktay; Gurcat Ahmet Gurhan; Kazanci Atilla; Senturk Salim; Bodur Ebru; Karaca Ebru Umay; Turkoglu Omer Faruk; Bavbek Murad;
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作者单位

Ankara Ataturk Educ &

Res Hosp Dept Neurosurg Ankara Turkey;

Ankara Ataturk Educ &

Res Hosp Dept Neurosurg Ankara Turkey;

Ankara Ataturk Educ &

Res Hosp Dept Neurosurg Ankara Turkey;

Koc Univ Hosp Dept Neurosurg Istanbul Turkey;

Hacettepe Univ Sch Med Dept Biochem Ankara Turkey;

Diskapi Yildirim Beyazit Educ &

Res Hosp Dept Phys Med &

Rehabil Ankara Turkey;

Ankara Ataturk Educ &

Res Hosp Dept Neurosurg Ankara Turkey;

Ankara Ataturk Educ &

Res Hosp Dept Neurosurg Ankara Turkey;

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原文格式 PDF
正文语种 eng
中图分类外科学各论;
关键词
Asiatic acid; Spinal cord injury; Trauma;

机译：亚洲酸;脊髓损伤;创伤;

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专利

1. Effect of Asiatic Acid on the Treatment of Spinal Cord Injury: An Experimental Study in Rats [J] . Gurcan Oktay, Gurcat Ahmet Gurhan, Kazanci Atilla, Turkish neurosurgery . 2017,第2期

机译：亚洲酸对脊髓损伤治疗的影响：大鼠实验研究
2. Experimental spinal cord injury induced an increase of extracellular ascorbic acid concentration in anesthetized rats: a microdialysis study. [J] . Tsai PJ, Chen WY, Tzeng SF, Clinica chimica acta: International journal of clinical chemistry and applied molecular biology . 2005,第1a2期

机译：实验性脊髓损伤导致麻醉大鼠的细胞外抗坏血酸浓度增加：一项微透析研究。
3. Use of Mometasone furoate in prolonged treatment of experimental spinal cord injury in mice: A comparative study of three different glucocorticoids [J] . Galuppo Maria, Rossi Antonietta, Giacoppo Sabrina, Pharmacological research: The official journal of The Italian Pharmacological Society . 2015,第Null期

机译：糠酸莫米他松在长期治疗小鼠实验性脊髓损伤中的应用：三种不同糖皮质激素的比较研究
4. TREATMENT STRATEGIES USING STEM CELLS IN EXPERIMENTAL SPINAL CORD INJURY [C] . Yvette S. Nout American College of Veterinary Internal Medicine Forum . 2008

机译：实验脊髓损伤中使用干细胞的治疗策略
5. Review of the pathogenesis and treatment of acute spinal cord injury and investigation into the use of urine 3-HPMA as a novel biomarker of secondary injury after acute spinal cord injury in the dog. [D] . Sangster, Andrea. 2014

机译：回顾急性脊髓损伤的发病机理和治疗方法，并探讨使用尿液3-HPMA作为犬急性脊髓损伤后继发性损伤的新型生物标志物。
6. Effect of VEGF Treatment on the Blood-Spinal Cord Barrier Permeability in Experimental Spinal Cord Injury: Dynamic Contrast-Enhanced Magnetic Resonance Imaging [O] . Chirag B. Patel, David M. Cohen, Pallavi Ahobila-Vajjula, -1

机译：VEGF处理对实验性脊髓损伤中血脊髓屏障通透性的影响：动态对比增强磁共振成像
7. An Experimental Study on the Treatment of Spinal Cord Injury in Rats by Tissue Engineering Method that Uses ADSCs Modified by BDNF and NT-3 Double Genes Combing the use of SFCS [O] . Wenchen Ji, Yusheng Qiu 2016

机译：组织工程方法治疗大鼠脊髓损伤的实验研究，用BDNF和NT-3双基因修饰ADSC梳理SFC的使用
8. Dynorphin A-Induced Rat Spinal Cord Injury: Evidence for Excitatory Amino AcidInvolvement in a Pharmacological Model of Ischemic Spinal Cord Injury [R] . Long, J. B., Rigamonti, D. D., Oleshansky, M. A., 1994

机译：强啡肽a诱导的大鼠脊髓损伤：缺血性脊髓损伤药理学模型中兴奋性氨基酸侵袭的证据

Effect of Asiatic Acid on the Treatment of Spinal Cord Injury: An Experimental Study in Rats

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