Advances in Acylation Methodologies Enabled by Oxyma-Based Reagents

摘要

The aim of this review is to cover recent advances in acylation chemistry (peptide, amide, and ester bond formation) in which ethyl 2-cyano-2-(hydroxyimino)acetate (Oxyma)-derived reagents are involved. The distinct applications of each class of Oxyma derivatives will be discussed and compared to the behavior of reputed standards in the field.