Synthesis and Applications of Diorganozinc Reagents: Beyond Diethylzinc

摘要

Diorganozinc reagents are unique nucleophiles because of the right balance between their nucleophilicity and basicity and because of the low reactivity of the byproducts of their reactions. These reagents possess very high functional-group tolerance and react sluggishly in the absence of a catalyst or the appropriate reaction conditions (Figure 1). For all these reasons, diorganozinc reagents can be viewed as privileged reagents in enantioselective catalysis.