Feasibility of the Von Willebrand disease PREVENT trial

Ragni Margaret V.; Machin Nicoletta; James Andra H.; Seaman Craig D.; Malec Lynn M.; Kessler Craig M.; Konkle Barbara A.; Kouides Peter A.; Neff Anne T.; Philipp Claire S.; Brooks Maria M.

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Feasibility of the Von Willebrand disease PREVENT trial

机译：Von Willebrand病的可行性阻止试验

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Background: Despite treatment, women with von Willebrand disease (VWD) have lower von Willebrand factor (VWF) levels and greater blood loss at delivery than controls. Current weight-based dosing does not account for the similar to 1.5-fold increase in blood volume in pregnancy.

机译：背景：尽管治疗，von Willebrand疾病（VWD）的女性在von Willebrand因子（VWF）水平下降，而且递送的血液损失大于对照。目前的体重剂量不占怀孕血量的类似于1.5倍。

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来源
《Thrombosis Research: An International Journal on Vascular Obstruction, Hemorrhage and Hemostasis》 |2017年第2017期|共6页
作者
Ragni Margaret V.; Machin Nicoletta; James Andra H.; Seaman Craig D.; Malec Lynn M.; Kessler Craig M.; Konkle Barbara A.; Kouides Peter A.; Neff Anne T.; Philipp Claire S.; Brooks Maria M.;
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作者单位

Univ Pittsburgh Med Ctr Pittsburgh PA 15213 USA;

Univ Pittsburgh Med Ctr Pittsburgh PA 15213 USA;

Duke Univ Med Ctr Durham NC USA;

Univ Pittsburgh Med Ctr Pittsburgh PA 15213 USA;

Univ Pittsburgh Med Ctr Pittsburgh PA 15213 USA;

Georgetown Univ Med Ctr Washington DC 20007 USA;

BloodWorks Northwest Seattle WA USA;

Rochester Gen Hosp Rochester NY 14621 USA;

Cleveland Clin Fdn 9500 Euclid Ave Cleveland OH 44195 USA;

Rutgers RobertWood Johnson Med Sch New Brunswick NJ USA;

Grad Sch Publ Hlth Pittsburgh PA USA;

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原文格式 PDF
正文语种 eng
中图分类神经病学;
关键词
Menorrhagia; Von Willebrand disease; Von Willebrand factor; Women's health;

机译：menorrhagia;来自Willebrand疾病;由Willebrand因素;妇女的健康;

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专利

1. Feasibility of the Von Willebrand disease PREVENT trial [J] . Ragni Margaret V., Machin Nicoletta, James Andra H., Thrombosis Research: An International Journal on Vascular Obstruction, Hemorrhage and Hemostasis . 2017,第期

机译：Von Willebrand病的可行性阻止试验
2. Efficacy and safety of factor VIII/von Willebrand's factor concentrate (Haemate-P) in preventing bleeding during surgery or invasive procedures in patients with von Willebrand disease | Haematologica [J] . M Franchini, G Rossetti, A Tagliaferri, Haematologica . 2003,第11期

机译：VIII因子/ von Willebrand因子浓缩物（Haemate-P）在预防von Willebrand病患者手术或侵入性手术中出血的功效和安全性|血液学
3. A randomised pilot trial of the anti-von Willebrand factor aptamer ARC1779 in patients with type 2b von Willebrand disease. [J] . Jilma B, Paulinska P, Jilma Stohlawetz P, Thrombosis and Haemostasis: Journal of the International Society on Thrombosis and Haemostasis . 2010,第3期

机译：抗von Willebrand因子适体ARC1779在2b型von Willebrand病患者中的随机先导试验。
4. A Model-Based Support for Diagnosing von Willebrand Disease [C] . Christopher Castaldello, Alessio Gubert, Federico Galvanin European Symposium on Computer Aided Process Engineering . 2017

机译：基于模型的诊断Von Willebrand疾病的支持
5. Biophysical Mechanisms Regulating Von Willebrand Disease, Arterial Thrombosis, and Deep Vein Thrombosis in Microfluidic Models of Vascular Injury [D] . Lehmann, Marcus. 2017

机译：血管损伤微流体模型中von Willebrand病，动脉血栓性疾病，动脉血栓形成和深静脉血栓形成的生物物理机制
6. Recombinant vs plasma-derived von Willebrand factor to prevent postpartum hemorrhage in von Willebrand disease [O] . Nicoletta Machin, Margaret V. Ragni 2020

机译：重组与等离子体衍生的von willebrand因素以防止von Willebrand病中的产后出血
7. Antifibrinolytic therapy for preventing oral bleeding in patients with haemophilia or Von Willebrand disease undergoing minor oral surgery or dental extractions [O] . Karin PM van Galen, Eveline T Engelen, Evelien P Mauser-Bunschoten, 2019

机译：防纤维蛋白溶解疗法预防血友病患者口服出血或von Willebrand疾病进行轻微口腔手术或牙科提取物

Feasibility of the Von Willebrand disease PREVENT trial

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