The risk of venous thromboembolism with aspirin compared to anticoagulants after hip and knee arthroplasty

摘要

Background: Recent guidelines include aspirin as an option to prevent venous thromboembolism(VTE) in selected patients undergoing hip or knee replacement surgery. However, the efficacy of aspirin after arthroplasty has not beenwell-defined, particularly in more contemporary patient populations. We compared rates of post-operative VTE between patients who received aspirin-only versus anticoagulants after hip or knee arthroplasty, using data from a large US-based administrative database.