Darunavir Population Pharmacokinetic Model Based on HIV Outpatient Data

Daskapan Alper; Tran Quynh T. D.; Cattaneo Dario; Gervasoni Cristina; Resnati Chiara; Stienstra Ymkje; Bierman Wouter F. W.; Kosterink Jos G. W.; van Der Werf Tjip S.; Proost Johannes H.; Alffenaar Jan-Willem C.; Touw Daniel J.

首页> 外文期刊>Therapeutic Drug Monitoring >Darunavir Population Pharmacokinetic Model Based on HIV Outpatient Data

【24h】

Darunavir Population Pharmacokinetic Model Based on HIV Outpatient Data

机译：基于艾滋病毒门诊数据的Darunavir人口药代动力学模型

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Background: Darunavir is a second-generation protease inhibitor and is registered for the treatment of HIV-1 infection. The aim of this study was to develop and validate a darunavir population pharmacokinetic model based on data from daily practice.

机译：背景：Darunavir是一种第二代蛋白酶抑制剂，并注册用于治疗HIV-1感染。本研究的目的是根据日常实践的数据制定和验证Darunavir人口药代动力学模型。

著录项

来源
《Therapeutic Drug Monitoring》 |2019年第1期|共7页
作者
Daskapan Alper; Tran Quynh T. D.; Cattaneo Dario; Gervasoni Cristina; Resnati Chiara; Stienstra Ymkje; Bierman Wouter F. W.; Kosterink Jos G. W.; van Der Werf Tjip S.; Proost Johannes H.; Alffenaar Jan-Willem C.; Touw Daniel J.;
展开▼
作者单位

Univ Groningen Univ Med Ctr Groningen Dept Clin Pharm &

Pharmacol POB 30-001 NL-9700 RB;

Univ Groningen Univ Med Ctr Groningen Dept Clin Pharm &

Pharmacol POB 30-001 NL-9700 RB;

Univ Hosp ASST Fatebenefratelli Sacco Unit Clin Pharmacol Milan Italy;

Univ Hosp ASST Fatebenefratelli Sacco Dept Infect Dis Milan Italy;

Univ Hosp ASST Fatebenefratelli Sacco Dept Infect Dis Milan Italy;

Univ Groningen Univ Med Ctr Groningen Dept Internal Med Infect Dis Groningen Netherlands;

Univ Groningen Univ Med Ctr Groningen Dept Internal Med Infect Dis Groningen Netherlands;

Univ Groningen Univ Med Ctr Groningen Dept Clin Pharm &

Pharmacol POB 30-001 NL-9700 RB;

Univ Groningen Univ Med Ctr Groningen Dept Internal Med Infect Dis Groningen Netherlands;

Univ Groningen Groningen Res Inst Pharm Unit Pharmacokinet Toxicol &

Targeting Groningen;

Univ Groningen Univ Med Ctr Groningen Dept Clin Pharm &

Pharmacol POB 30-001 NL-9700 RB;

Univ Groningen Univ Med Ctr Groningen Dept Clin Pharm &

Pharmacol POB 30-001 NL-9700 RB;

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类生药学（天然药物学）;
关键词
pharmacokinetics; protease inhibitor; HIV-1 infection; therapeutic drug monitoring;

机译：药代动力学;蛋白酶抑制剂;HIV-1感染;治疗药物监测;

相似文献

外文文献
中文文献
专利

1. Darunavir Population Pharmacokinetic Model Based on HIV Outpatient Data [J] . Daskapan Alper, Tran Quynh T. D., Cattaneo Dario, Therapeutic Drug Monitoring . 2019,第1期

机译：基于艾滋病毒门诊数据的Darunavir人口药代动力学模型
2. Simultaneous population pharmacokinetic modelling of darunavir and ritonavir Once daily in HIV‐infected patients: evaluation of lower ritonavir dose [J] . L Dickinson, A Jackson, L Garvey, Journal of the International Aids Society . 2012,第Suppla2期

机译：艾滋病毒感染患者中达那那韦和利托那韦同时人群药代动力学建模：每天一次：评估较低的利托那韦剂量
3. Population pharmacokinetic modelling of once-daily ritonavir-boosted darunavir in HIV-infected patients [J] . L Dickinson, AGA Jackson, LJ Garvey, Journal of the International Aids Society . 2010,第Suppla4期

机译：艾滋病毒感染患者曾经每日Ritonavir-Boosted Darunavir的人口药代动力学建模
4. KINETIC AND MECHANISTIC DATA NEEDS FOR A HUMAN PHSIOLOGICALLY BASED PHARMACOKINETIC (PBPK) MODEL FOR ACRYLAMIDE: Pharmacokinetic Model for Acrylamide [C] . Melvin E. Andersen, Joseph Scimeca, Stephen S. Olin, ACS Symposium on Chemistry and Safety of Acrylamide in Food . 2005

机译：用于丙烯酰胺的人体氏药代理（PBPK）模型的动力学和机械数据需求：丙烯酰胺的药代动力学模型
5. Applications of Physiologically Based Pharmacokinetic Modelling to Prediction of the Likelihood of Metabolic Drug Interactions in Paediatric Population and Studying Disparities in Pharmacokinetics Between Children and Adults [D] . Salem, Farzaneh. 2014

机译：基于生理的药代动力学模型在小儿人群中代谢药物相互作用的可能性预测和研究儿童与成人之间药代动力学差异的应用
6. Darunavir Population Pharmacokinetic Model Based on HIV Outpatient Data [O] . Alper Daskapan, Quynh T.D. Tran, Dario Cattaneo, -1

机译：基于HIV门诊数据的Darunavir人群药代动力学模型
7. Exploration of Reduced Doses and Short-Cycle Therapy for Darunavir/Cobicistat in Patients with HIV Using Population Pharmacokinetic Modeling and Simulations [O] . Gabriel Stillemans, Leila Belkhir, Bernard Vandercam, 2020

机译：使用人口药代动力学建模和模拟对艾滋病毒患者Darunavir / Cobicistat减少剂量和短循环治疗的探讨

Darunavir Population Pharmacokinetic Model Based on HIV Outpatient Data

摘要

著录项

相似文献

相关主题

期刊订阅