Pharmacokinetic Comparison of Two Mycophenolate Mofetil Formulations in Kidney Transplant Recipients

Zhang Jun; Luo YongGang; Zhu ZhenFeng; Feng GuiWen; Sun Zhi; Zhang XiaoJian

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Pharmacokinetic Comparison of Two Mycophenolate Mofetil Formulations in Kidney Transplant Recipients

机译：肾移植受者两种霉酚酸酯制剂的药代动力学比较

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Background: The aim of this study was to investigate and compare the pharmacokinetic (PK) characteristics of mycophenolate mofetil (MMF) capsule and MMF dispersible tablet by detecting the active metabolite of mycophenolic acid (MPA) in Chinese kidney transplant recipients.

机译：背景：本研究的目的是通过检测中华肾移植受体中的肌霉素（MPA）的活性代谢物来研究和比较霉酚酸酯MOFETIL（MMF）胶囊（MMF）胶囊和MMF可分散片的药代动力学（PK）特征。

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来源
《Therapeutic Drug Monitoring》 |2018年第5期|共6页
作者
Zhang Jun; Luo YongGang; Zhu ZhenFeng; Feng GuiWen; Sun Zhi; Zhang XiaoJian;
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作者单位

Zhengzhou Univ Affiliated Hosp 1 Dept Pharm 1 Jianshe East Rd Zhengzhou 450052 Henan Peoples;

Zhengzhou Univ Affiliated Hosp 1 Integrated Intens Care Unit Zhengzhou Henan Peoples R China;

Zhengzhou Univ Affiliated Hosp 1 Dept Pharm 1 Jianshe East Rd Zhengzhou 450052 Henan Peoples;

Zhengzhou Univ Affiliated Hosp 1 Renal Transplantat Zhengzhou Henan Peoples R China;

Zhengzhou Univ Affiliated Hosp 1 Dept Pharm 1 Jianshe East Rd Zhengzhou 450052 Henan Peoples;

Zhengzhou Univ Affiliated Hosp 1 Dept Pharm 1 Jianshe East Rd Zhengzhou 450052 Henan Peoples;

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原文格式 PDF
正文语种 eng
中图分类生药学（天然药物学）;
关键词
mycophenolate mofetil; mycophenolic acid; pharmacokinetic; renal transplantation;

机译：霉酚酸酯;霉菌酸;药代动力学;肾移植;

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专利

1. Pharmacokinetic Comparison of Two Mycophenolate Mofetil Formulations in Kidney Transplant Recipients [J] . Zhang Jun, Luo YongGang, Zhu ZhenFeng, Therapeutic Drug Monitoring . 2018,第5期

机译：肾移植受者两种霉酚酸酯制剂的药代动力学比较
2. Comparative pharmacokinetic study of two mycophenolate mofetil formulations in stable kidney transplant recipients [J] . Sunder-PlassmannG., ReinkeP., RathT., Transplant international : . 2012,第6期

机译：两种麦考酚酸酯制剂在稳定的肾移植受者中的比较药代动力学研究
3. Population Pharmacokinetics of Mycophenolic Acid : A Comparison between Enteric-Coated Mycophenolate Sodium and Mycophenolate Mofetil in Renal Transplant Recipients. [J] . de-Winter BC, van-Gelder T, Glander P, Clinical pharmacokinetics . 2008,第12期

机译：麦考酚酸的群体药代动力学：肾脏移植接受者的肠溶麦考酚酸钠和麦考酚酯之间的比较。
4. Pre-Transplant Mycophenolate Mofetil Pharmacokinetics in Mexican Children [C] . Villa, M., Gonzalez R., Western Pharmacology Society . 2011

机译：在墨西哥儿童预移植霉霉素Mofetil药代动力学
5. Characterization of renal anionic drug transport capacity in kidney transplant recipients with persistent BK viremia: Pharmacokinetic and pharmacodynamic studies of cidofovir. [D] . Momper, Jeremiah D. 2011

机译：持续性BK病毒血症的肾脏移植受者中肾脏阴离子药物转运能力的表征：西多福韦的药代动力学和药效学研究。
6. Comparative pharmacokinetic study of two mycophenolate mofetil formulations in stable kidney transplant recipients [O] . Gere Sunder-Plassmann, Petra Reinke, Thomas Rath, -1

机译：两种麦考酚酸酯制剂在稳定的肾移植受者中的比较药代动力学研究
7. Comparative pharmacokinetic study of two mycophenolate mofetil formulations in stable kidney transplant recipients [O] . Gere Sunder‐Plassmann, Petra Reinke, Thomas Rath, 2012

机译：稳定肾移植受体中两种霉酚酸酯制剂的比较药代动力学研究

Pharmacokinetic Comparison of Two Mycophenolate Mofetil Formulations in Kidney Transplant Recipients

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