Is Ongoing Anticholinergic Burden Associated With Greater Cognitive Decline and Dementia Severity in Mild to Moderate Alzheimer's Disease?

Dyer Adam H.; Murphy Claire; Segurado Ricardo; Lawlor Brian; Kennelly Sean P.

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Is Ongoing Anticholinergic Burden Associated With Greater Cognitive Decline and Dementia Severity in Mild to Moderate Alzheimer's Disease?

机译：正在进行的抗胆碱能负担与更高的认知下降和痴呆症患者在轻度到中度阿尔茨海默病中有关吗？

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Background: Use of anticholinergic medication is associated with an increased risk of cognitive impairment and/or dementia. Despite this, the impact of continuing medication with anticholinergic properties in those diagnosed with Alzheimer's Disease (AD) is not clear.

机译：背景：抗胆碱能药物的使用与认知障碍和/或痴呆的风险增加有关。尽管如此，持续用药在患有阿尔茨海默病（AD）患者中的抗胆碱能性能的影响尚不清楚。

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《The journals of gerontology.Series A. Biological sciences and medical sciences》 |2020年第5期|共8页
作者
Dyer Adam H.; Murphy Claire; Segurado Ricardo; Lawlor Brian; Kennelly Sean P.;
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作者单位

Tallaght Univ Hosp Dept Age Related Healthcare Dublin Ireland;

Tallaght Univ Hosp Dept Age Related Healthcare Dublin Ireland;

Univ Coll Dublin Ctr Support &

Training Anal &

Res CSTAR Dublin Ireland;

Trinity Coll Dublin Sch Med Dept Med Gerontol Dublin Ireland;

Tallaght Univ Hosp Dept Age Related Healthcare Dublin Ireland;

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原文格式 PDF
正文语种 eng
中图分类老年病学;
关键词
Alzheimers; Drug related; Medication; Cognitive aging;

机译：阿尔茨海默斯;药物相关;药物;认知老龄化;

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1. Is Ongoing Anticholinergic Burden Associated With Greater Cognitive Decline and Dementia Severity in Mild to Moderate Alzheimer's Disease? [J] . Dyer Adam H., Murphy Claire, Segurado Ricardo, The journals of gerontology.Series A. Biological sciences and medical sciences . 2020,第5期

机译：正在进行的抗胆碱能负担与更高的认知下降和痴呆症患者在轻度到中度阿尔茨海默病中有关吗？
2. Sexual dimorphism in the association of APOE epsilon 4 genotype with cognitive decline and dementia progression in mild-to-moderate Alzheimer disease [J] . Trends in Ecology & Evolution . 2020,第6期

机译：epose epsilon 4基因型的性二态性在轻度至中等阿尔茨海默病中具有认知下降和痴呆进展的基因型
3. Sexual dimorphism in the association of APOE ε4 genotype with cognitive decline and dementia progression in mild‐to‐moderate Alzheimer disease [J] . International journal of geriatric psychiatry . 2020,第6期

机译：ε4基因型关联性的性二态性与中温含累的阿尔茨米尔病中的认知下降和痴呆进展
4. Early Detection of Mild Cognitive Impairment and Mild Alzheimer's Disease in Elderly using CBF Activation during Verbally-based Cognitive Tests [C] . Shohei Kato, Hidetoshi Endo, Risako Nagata, International Conference on Health Informatics . 2014

机译：在基于口头的认知测试期间使用CBF激活的老年人患者轻度认知障碍和轻度阿尔茨海默病的早期发现
5. The effect of anticholinergic burden on functional outcomes in patients with moderate to severe Alzheimer's disease. [D] . Dharia, Sheetal Prabodh. 2010

机译：抗胆碱能负担对中度至重度阿尔茨海默氏病患者功能结局的影响。
6. Telomere shortening reflecting physical aging is associated with cognitive decline and dementia conversion in mild cognitive impairment due to Alzheimer’s disease [O] . Seong-Ho Koh, Seong Hye Choi, Jee Hyang Jeong, 2020

机译：端粒缩短反映身体衰老与阿尔茨海默氏病引起的轻度认知障碍中的认知能力下降和痴呆转化有关
7. Telomere shortening reflecting physical aging is associated with cognitive decline and dementia conversion in mild cognitive impairment due to Alzheimer’s disease [O] . Seong-Ho Koh, Seong Hye Choi, Jee Hyang Jeong, 2020

机译：端粒体缩短反射物理衰老与患有阿尔茨海默病引起的轻度认知障碍中的认知下降和痴呆症转化有关
8. Considerations for the Design of a Systemic Review of Interventions for Preventing Clinical Alzheimer’s-Type Dementia, Mild Cognitive Impairment, and Age-Related Cognitive Decline. Letter Report. [R] . 2015

机译：设计预防临床阿尔茨海默氏型痴呆，轻度认知障碍和年龄相关认知衰退的干预系统评价的考虑因素。信报告。

Is Ongoing Anticholinergic Burden Associated With Greater Cognitive Decline and Dementia Severity in Mild to Moderate Alzheimer's Disease?

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