Plasma Klotho and Frailty in Older Adults: Findings From the InCHIANTI Study

Shardell Michelle; Semba Richard D.; Kalyani Rita R.; Bandinelli Stefania; Prather Aric A.; Chia Chee W.; Ferrucci Luigi

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Plasma Klotho and Frailty in Older Adults: Findings From the InCHIANTI Study

机译：等离子Klotho和老年人的脆弱：从春馨的研究中发现

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Background: The hormone klotho, encoded by the gene klotho, is primarily expressed in the kidney and choroid plexus of the brain. Higher klotho concentrations have been linked to better physical performance; however, it is unknown whether klotho relates to frailty status in older adults.

机译：背景：由基因klotho编码的激素Klotho主要在肾脏和脉络膜丛中表达的大脑。较高的Klotho浓度与更好的物理性能相关联; 然而，克罗托是否涉及老年人的脆弱地位是未知的。

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《The journals of gerontology.Series A. Biological sciences and medical sciences 》 |2019年第7期| 共6页
作者
Shardell Michelle; Semba Richard D.; Kalyani Rita R.; Bandinelli Stefania; Prather Aric A.; Chia Chee W.; Ferrucci Luigi;
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作者单位

NIA Translat Gerontol Branch Baltimore MD 21224 USA;

Johns Hopkins Med Inst Wilmer Eye Inst Baltimore MD 21205 USA;

Johns Hopkins Med Inst Dept Med Baltimore MD 21205 USA;

Azienda Sanit Firenze Geriatr Rehabil Unit Florence Italy;

Univ Calif San Francisco Dept Psychiat San Francisco CA 94143 USA;

NIA Translat Gerontol Branch Baltimore MD 21224 USA;

NIA Translat Gerontol Branch Baltimore MD 21224 USA;

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原文格式 PDF
正文语种 eng
中图分类老年病学 ;
关键词
Biomarkers; Endocrinology; Frailty syndrome; Epidemiology;

机译：生物标志物;内分泌学;体育综合征;流行病学;

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1. Plasma Klotho and Frailty in Older Adults: Findings From the InCHIANTI Study [J] . Shardell Michelle, Semba Richard D., Kalyani Rita R., The journals of gerontology.Series A. Biological sciences and medical sciences . 2019 ,第7期

机译：等离子Klotho和老年人的脆弱：从春馨的研究中发现
2. Serum 25-Hydroxyvitamin D, Plasma Klotho, and Lower-Extremity Physical Performance Among Older Adults: Findings From the InCHIANTI Study [J] . Shardell Michelle, Semba Richard D., Kalyani Rita R., The journals of gerontology.Series A. Biological sciences and medical sciences . 2015 ,第9期

机译：老年人血清25-羟维生素D，血浆Klotho和下肢的身体表现：来自INCHIANTI研究的结果
3. Relationship of low plasma klotho with poor grip strength in older community-dwelling adults: the InCHIANTI study. [J] . Richard D Semba, Anne R Cappola, Kai Sun, European journal of applied physiology . 2012 ,第4期

机译：InCHIANTI研究显示，血浆血浆Klotho与老年人的较差抓地力有关。
4. Ambient Air Pollution in Relation to Diabetes and Hemoglobin A1c Biomarker in China: A Cross-Sectional Study with Findings from National Representative Data: WHO Study on Global Ageing and Adult Health (SAGE) Wave 1 [C] . Mono Elbarbary Joint annual meeting of the International Society of Exposure Science and the International Society for Environmental Epidemiology . 2018

机译：与中国糖尿病和血红蛋白A1c生物标志物有关的环境空气污染：一项具有国家代表性数据的跨部门研究：世卫组织全球老龄化和成人健康研究（SAGE）第一轮
5. From nutritional status to mental health: Evidence of a relation of iron status to cognitive performance and depressive symptoms in older adults from the InCHIANTI study. [D] . Chen, Lenis Pangwun. 2013

机译：从营养状况到心理健康：InCHIANTI研究表明，铁的状况与老年人的认知能力和抑郁症状有关。
6. Plasma Klotho and Frailty in Older Adults: Findings From the InCHIANTI Study [O] . Michelle Shardell, Richard D Semba, Rita R Kalyani, -1

机译：老年人血浆Klotho和身体虚弱：来自INCHIANTI研究的发现
7. Plasma Klotho and Frailty in Older Adults: Findings From the InCHIANTI Study [O] . Michelle Shardell, Richard D Semba, Rita R Kalyani, 2017

机译：老年人的血浆Klotho和Freailty：从春馨的研究中发现

Plasma Klotho and Frailty in Older Adults: Findings From the InCHIANTI Study

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