首页> 外文期刊>The journal of pain: official journal of the American Pain Society >Psychological Characteristics and Pain Frequency Are Associated With Experimental Pain Sensitivity in Pediatric Patients With Sickle Cell Disease
【24h】

Psychological Characteristics and Pain Frequency Are Associated With Experimental Pain Sensitivity in Pediatric Patients With Sickle Cell Disease

机译:心理特征和疼痛频率与小儿患者患者镰状细胞病的实验性疼痛敏感有关

获取原文
获取原文并翻译 | 示例
       

摘要

Sickle cell disease (SCD) is associated with episodes of severe vaso-occlusive pain beginning in infancy with a subset of patients with SCD transitioning to chronic pain. Response to experimental pain using quantitative sensory testing in these patients suggests altered pain processing. The objectives of this study were to characterize sensitivity to multiple modalities of experimental pain stimuli and to interrogate the relationship of psychological covariates, clinical pain burden, and pain-related outcomes to experimental pain sensitivity in children with SCD compared with healthy individuals of similar age and sex. Cross-sectional assessments of psychological characteristics were performed, and quantitative sensory testing methods were used to measure experimental pain sensitivity in children age 8 to 21 years. Anxiety, depressive symptoms, catastrophizing, and somatization were found to be associated with increased sensitivity to experimental pain stimuli. Increased frequency of painful episodes in SCD was associated with decreased sensitivity to heat pain and decreased mechanical temporal summation. These data suggest that careful consideration be given to psychological factors, age, sex, and clinical burden of pain when studying response to experimental pain in SCD.
机译:镰状细胞疾病(SCD)与婴儿期开始的严重血管闭塞疼痛的发作有关,其患者的SCD转换到慢性疼痛的患者。在这些患者中使用定量感官测试的实验疼痛的反应表明疼痛加工改变。本研究的目的是表征对多种实验性疼痛刺激模式的敏感性,并与SCD的儿童儿童的实验疼痛敏感性询问与SCD的儿童的实验性疼痛敏感性的关系相比性别。进行了心理特征的横截面评估,使用定量感官检测方法测量8至21岁儿童的实验疼痛敏感性。发现焦虑,抑郁症状,灾难性和躯体化与对实验性疼痛刺激的敏感性增加有关。 SCD中疼痛发作的频率增加与热疼痛的敏感性降低有关,并且机械时间求和降低。这些数据表明,在研究SCD的实验疼痛的反应时,仔细考虑疼痛的心理因素,年龄,性别和临床负担。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号