Evaluation of Lipocalin-2 as a Biomarker of Periprosthetic Joint Infection

Vergara Andrea; Fernandez-Pittol Mariana J.; Munoz-Mahamud Ernesto; Morata Laura; Bosch Jordi; Vila Jordi; Soriano Alex; Casals-Pascual Climent

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Evaluation of Lipocalin-2 as a Biomarker of Periprosthetic Joint Infection

机译：脂素-2的评价为PeriproSthetth关节感染的生物标志物

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摘要

Background: Periprosthetic joint infection (PJI) remains a major clinical challenge. In this study, we evaluated the diagnostic performance of lipocalin-2 (LCN2), a well-characterized neutrophil protein, in synovial fluid to discriminate PJI and aseptic implant failure.

机译：背景：PeriproSthetth关节感染（PJI）仍然是一个重大的临床挑战。在该研究中，我们评估了滑膜液中脂素-2（LCN2），在滑膜中的良好表现嗜中性粒细胞蛋白的诊断性能，以区分PJI和无菌植物植入失败。

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来源
《The Journal of arthroplasty》 |2019年第1期|共3页
作者
Vergara Andrea; Fernandez-Pittol Mariana J.; Munoz-Mahamud Ernesto; Morata Laura; Bosch Jordi; Vila Jordi; Soriano Alex; Casals-Pascual Climent;
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作者单位

Univ Barcelona Hosp Clin Barcelona CDB Dept Clin Microbiol Barcelona Spain;

Univ Barcelona Hosp Clin Barcelona CDB Dept Clin Microbiol Barcelona Spain;

Inst Clin Especialidades Med &

Quirurg ICEMEQ Dept Orthoped Surg &

Traumatol Barcelona Spain;

Univ Barcelona Inst Clin Med &

Dermatol ICMID Hosp Clin Barcelona IDIBAPS Dept Infect Dis;

Univ Barcelona Hosp Clin Barcelona CDB Dept Clin Microbiol Barcelona Spain;

Univ Barcelona Hosp Clin Barcelona CDB Dept Clin Microbiol Barcelona Spain;

Univ Barcelona Inst Clin Med &

Dermatol ICMID Hosp Clin Barcelona IDIBAPS Dept Infect Dis;

Univ Barcelona Hosp Clin Barcelona CDB Dept Clin Microbiol Barcelona Spain;

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原文格式 PDF
正文语种 eng
中图分类骨科学（运动系疾病、矫形外科学）;
关键词
lipocalin-2; periprosthetic joint infection; aseptic implant failure; neutrophil gelatinase-associated lipocalin; biomarker;

机译：Lipocalin-2;PeriproSthetth关节感染;无菌植物失败;中性粒细胞明胶酶相关的脂素;生物标志物;

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专利

1. Evaluation of Lipocalin-2 as a Biomarker of Periprosthetic Joint Infection [J] . Vergara Andrea, Fernandez-Pittol Mariana J., Munoz-Mahamud Ernesto, The Journal of arthroplasty . 2019,第1期

机译：脂素-2的评价为PeriproSthetth关节感染的生物标志物
2. What is the performance of novel synovial biomarkers for detecting periprosthetic joint infection in the presence of inflammatory joint disease? X-ref [J] . Bone & joint 360 . 2021,第2期

机译：新型滑膜生物标志物的表现是什么，用于检测炎症关节疾病存在下的颅脑关节感染？ X-Ref.
3. Serum biomarkers in periprosthetic joint infections [J] . A. Saleh, J. George, M. Faour, Bone & Joint Research . 2018,第1期

机译：人工关节周围感染的血清生物标志物
4. Pilot In Vivo Evaluation of a Resorbable, Antibiotic-Eluting Bone Void Filler to Prevent Periprosthetic Joint Infection [C] . Kristofer D. Sinclair, Amanda Brooks, Zachary Ferrell, Society for Biomaterials annual meeting and exposition . 2015

机译：可吸收的，抗生素洗脱的骨空隙填充物预防假体周围关节感染的先导体内评估
5. Protein Discovery in African Trypanosomes: Studying Differential Protein Expression Throughout the Parasite life Cycle and Identification of Candidate Biomarkers for Diagnosing Trypanosome Infections. [D] . Eyford, Brett Alexander. 2013

机译：在非洲锥虫中发现蛋白质：研究整个寄生虫生命周期中差异蛋白的表达以及诊断锥虫感染的候选生物标志物的鉴定。
6. Serum biomarkers in periprosthetic joint infections [O] . A. Saleh, J. George, M. Faour, 2018

机译：人工关节周围感染的血清生物标志物
7. Serum globulin and albumin to globulin ratio as potential diagnostic biomarkers for periprosthetic joint infection: a retrospective review [O] . Yongyu Ye, Weishen Chen, Minghui Gu, 2020

机译：血清球蛋白和白蛋白对球蛋白的比例作为潜在的诊断生物标志物，用于治疗突发性关节感染：回顾性审查

Evaluation of Lipocalin-2 as a Biomarker of Periprosthetic Joint Infection

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