Surveillance for azole resistance in clinical and environmental isolates of Aspergillus fumigatus in Australia and cyp51A homology modelling of azole-resistant isolates

Talbot Jessica J.; Subedi Shradha; Halliday Catriona L.; Hibbs David E.; Lai Felcia; Lopez-Ruiz Francisco J.; Harper Lincoln; Park Robert F.; Cuddy William S.; Biswas Chayanika; Cooley Louise; Carter Dee; Sorrell Tania C.; Barrs Vanessa R.; Chen Sharon C. -A.

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Surveillance for azole resistance in clinical and environmental isolates of Aspergillus fumigatus in Australia and cyp51A homology modelling of azole-resistant isolates

机译：澳大利亚Aspergillus Fumigatus临床和环境分离株的抗唑抗性监测及抗唑抗性分离物的同源性建模

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Background: The prevalence of azole resistance in Aspergillus fumigatus is uncertain in Australia. Azole exposure may select for resistance. We investigated the frequency of azole resistance in a large number of clinical and environmental isolates.

机译：背景：在澳大利亚的烟草菌灰抗唑抗性的患病率不确定。唑曝光可以选择电阻。我们调查了大量临床和环境分离物中唑抗性的频率。

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《The Journal of Antimicrobial Chemotherapy》 |2018年第9期|共5页
作者
Talbot Jessica J.; Subedi Shradha; Halliday Catriona L.; Hibbs David E.; Lai Felcia; Lopez-Ruiz Francisco J.; Harper Lincoln; Park Robert F.; Cuddy William S.; Biswas Chayanika; Cooley Louise; Carter Dee; Sorrell Tania C.; Barrs Vanessa R.; Chen Sharon C. -A.;
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作者单位

Univ Sydney Sydney Sch Vet Sci Fac Sci Sydney NSW Australia;

Univ Sydney Westmead Hosp Ctr Infect Dis Westmead NSW Australia;

Univ Sydney Westmead Hosp Ctr Infect Dis Westmead NSW Australia;

Univ Sydney Fac Pharm Sydney NSW Australia;

Univ Sydney Fac Pharm Sydney NSW Australia;

Curtin Univ Sch Mol &

Life Sci Ctr Crop &

Dis Management Bentley WA Australia;

Curtin Univ Sch Mol &

Life Sci Ctr Crop &

Dis Management Bentley WA Australia;

Univ Sydney Plant Breeding Inst Cobbitty Judith &

David Coffey Chair Sustainable Agr Sydney NSW;

Elizabeth Macarthur Agr Inst NSW Dept Primary Ind Menangle Australia;

Univ Sydney Westmead Hosp Ctr Infect Dis Westmead NSW Australia;

Royal Hobart Hosp Dept Microbiol &

Infect Dis Hobart Tas Australia;

Univ Sydney Marie Bashir Inst Infect Dis &

Biosecur Westmead NSW Australia;

Univ Sydney Marie Bashir Inst Infect Dis &

Biosecur Westmead NSW Australia;

Univ Sydney Sydney Sch Vet Sci Fac Sci Sydney NSW Australia;

Univ Sydney Marie Bashir Inst Infect Dis &

Biosecur Westmead NSW Australia;

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正文语种 eng
中图分类治疗学;
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1. Surveillance for azole resistance in clinical and environmental isolates of Aspergillus fumigatus in Australia and cyp51A homology modelling of azole-resistant isolates [J] . Talbot Jessica J., Subedi Shradha, Halliday Catriona L., The Journal of Antimicrobial Chemotherapy . 2018,第9期

机译：澳大利亚Aspergillus Fumigatus临床和环境分离株的抗唑抗性监测及抗唑抗性分离物的同源性建模
2. Azole resistance in Aspergillus fumigatus isolates from the ARTEMIS global surveillance study is primarily due to the TR/L98H mutation in the cyp51A gene. [J] . Lockhart SR, Frade JP, Etienne KA, Antimicrobial agents and chemotherapy. . 2011,第9期

机译：来自ARTEMIS全球监测研究的烟曲霉分离株的偶氮抗药性主要归因于cyp51A基因中的TR / L98H突变。
3. Non- cyp51A Azole-Resistant Aspergillus fumigatus Isolates with Mutation in HMG-CoA Reductase [J] . Daisuke Hagiwara, Teppei Arai, Hiroki Takahashi, Emerging Infectious Diseases . 2018,第10期

机译：非cyp51A耐唑类烟曲霉分离株具有HMG-CoA还原酶突变
4. Study of Drug Resistance in Clinical Isolates of Enterococci with special reference to high level aminoglycoside resistance, beta lactamase production and lateral transfer of drug resistance [C] . M.G. Karmarkar, Edwin S. Gershom, Santosh Kaul, Lancefield International Symposium on Streptococci and Streptococcal Diseases . 2006

机译：肠球菌临床分离株的耐药性研究，特别是高水平氨基糖苷抵抗，β内酰胺酶生产和耐药性横向转移
5. Homology modeling and biochemical characterization of substrate binding to cyclooxygenase - peroxidase superfamily members Aspergillus fumigatus 5,8-linoleate diol synthase and Gracilaria vermiculophylla cyclooxygenase. [D] . Nandagiri, Ritwik. 2014

机译：底物结合环加氧酶-过氧化物酶超家族成员烟曲霉5，8-亚油酸二醇合酶和Gra草ver叶环加氧酶的同源性建模和生化特征。
6. Azole Resistance in Aspergillus fumigatus Isolates from the ARTEMIS Global Surveillance Study Is Primarily Due to the TR/L98H Mutation in the cyp51A Gene [O] . Shawn R. Lockhart, João P. Frade, Kizee A. Etienne, 2011

机译：来自ARTEMIS全球监测研究的烟曲霉分离株的偶氮抗性主要归因于cyp51A基因的TR / L98H突变
7. Surveillance for azole resistance in clinical and environmental isolates of Aspergillus fumigatus in Australia and cyp51A homology modelling of azole-resistant isolates [O] . Jessica J Talbot, Shradha Subedi, Catriona L Halliday, 2018

机译：澳大利亚Aspergillus Fumigatus临床和环境分离株抗唑抗性的监测及抗唑抗性隔离物的同源性建模

Surveillance for azole resistance in clinical and environmental isolates of Aspergillus fumigatus in Australia and cyp51A homology modelling of azole-resistant isolates

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