Association of-330 interleukin-2 gene polymorphism with oral cancer

摘要

Background & objectives: Cytokines play an important role in the development of cancer. Several single-nucleotide polymorphisms (SNPs) of cytokine genes have been reported to be associated with the development and severity of inflammatory diseases and cancer predisposition. This study was undertaken to evaluate a possible association of interleukin 2 (IL-2) (-330A C) gene polymorphisms with the susceptibility to oral cancer.