THE EFFECT OF CARDIAC RESYNCHRONIZATION THERAPY ON OUTCOMES IN WOMEN: A SUBSTUDY OF THE RESYNCHRONIZATON FOR AMBULATORY HEART FAILURE TRIAL

摘要

BACKGROUND: Cardiac resynchronization therapy defibrillator (CRT-D) has demonstrated reduced mortality and heart failure hospitalizations in patients with left ventricular dysfunction and left bundle branch block (LBBB). Prior studies have demonstrated that women may benefit more than men from CRT-D. We sought to further evaluate this hypothesis in a post hoc analysis of the Resynchronization for Ambulatory Heart Failure Trial (RAFT) on mortality and heart failure hospitalization. The RAFT study has the advantage of longer duration of follow up than any of the other studies on CRT-D.