miR-124 regulates EMT based on ZEB2 target to inhibit invasion and metastasis in triple-negative breast cancer

Jia Hong; Sang Meixiang; Liu Fei; Ai Ning; Geng Cuizhi

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miR-124 regulates EMT based on ZEB2 target to inhibit invasion and metastasis in triple-negative breast cancer

机译：MiR-124根据Zeb2靶标调节EMT，以抑制三阴性乳腺癌中的侵袭和转移

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Background: Triple-negative breast cancer (TNBC) is highly invasive and aggressive and lacks specific molecular targets to improve the prognosis. MicroRNAs (miRNAs) serve a role in promoting and suppressing tumors in various types of malignant cancer, including TNBC. However, the regulatory mechanism of miR-124 in TNBC has still remains unclear.

机译：背景：三重阴性乳腺癌（TNBC）是高度侵入性和侵蚀性，缺乏特定的分子靶标以改善预后。 microRNAs（miRNA）用于促进和抑制各种类型恶性癌症的肿瘤，包括TNBC。然而，TNBC中miR-124的监管机制仍然尚不清楚。

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来源
《Pathology Research and Practice 》 |2019年第4期| 共8页
作者
Jia Hong; Sang Meixiang; Liu Fei; Ai Ning; Geng Cuizhi;
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作者单位

Hebei Med Univ Hosp 2 Dept Gen Surg Shijiazhuang Hebei Peoples R China;

Hebei Med Univ Hosp 4 Med Res Ctr Shijiazhuang Hebei Peoples R China;

Hebei Med Univ Hosp 4 Med Res Ctr Shijiazhuang Hebei Peoples R China;

Hebei Med Univ Hosp 4 Dept Intervent Radiol Shijiazhuang Hebei Peoples R China;

Hebei Med Univ Hosp 4 Dept Gen Surg Shijiazhuang Hebei Peoples R China;

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原文格式 PDF
正文语种 eng
中图分类病理学 ;
关键词
miR-124; ZEB2; epithelial-mesenchymal transition; Triple-negative breast cancer; Invasion; Metastasis;

机译：miR-124;zeb2;上皮 - 间充质转换;三阴性乳腺癌;入侵;转移;

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专利

1. miR-124 regulates EMT based on ZEB2 target to inhibit invasion and metastasis in triple-negative breast cancer [J] . Jia Hong, Sang Meixiang, Liu Fei, Pathology Research and Practice . 2019 ,第4期

机译：MiR-124根据Zeb2靶标调节EMT，以抑制三阴性乳腺癌中的侵袭和转移
2. MiR-6838-5p suppresses cell metastasis and the EMT process in triple-negative breast cancer by targeting WNT3A to inhibit the Wnt pathway [J] . Liu Guozhu, Wang Ping, Zhang Hao The journal of gene medicine . 2019 ,第12期

机译：MiR-6838-5P通过靶向Wnt3a抑制Wnt3a来抑制三阴性乳腺癌中的细胞转移和EMT过程，以抑制WNT途径
3. Silencing beta 3 Integrin by Targeted ECO/siRNA Nanoparticles Inhibits EMT and Metastasis of Triple-Negative Breast Cancer [J] . Parvani Jenny G., Gujrati Maneesh D., Mack Margaret A., Cancer research: The official organ of the American Association for Cancer Research, Inc . 2015 ,第11期

机译：靶向Eco / siRNA纳米粒子的沉默β3整合蛋白抑制了三阴性乳腺癌的EMT和转移
4. ERβ regulates miR-21 expression and inhibits invasion and metastasis in cancer cells [C] . Junmei Tian, Zhenzhen Tu, Yueqing Gu Biophotonics and immune responses VII. . 2012

机译：ERβ调节miR-21表达并抑制癌细胞的侵袭和转移
5. The Role of Tumor-Associated Macrophages in Triple-Negative Breast Cancer Invasion and Metastasis [D] . Rabe, Daniel Christopher. 2017

机译：肿瘤相关巨噬细胞在三阴性乳腺癌侵袭和转移中的作用
6. MicroRNA-590-3p inhibits invasion and metastasis in triple-negative breast cancer by targeting Slug [O] . Meisi Yan, Leiguang Ye, Xinxin Feng, 2020

机译：MicroRNA-590-3p通过靶向Slug抑制三阴性乳腺癌的侵袭和转移
7. Silencing β3 Integrin by Targeted ECO/siRNA Nanoparticles Inhibits EMT and Metastasis of Triple-Negative Breast Cancer [O] . Jenny G. Parvani, Maneesh D. Gujrati, Margaret A. Mack, 2015

机译：靶向Eco / siRNA纳米粒子的沉默β3整合蛋白抑制了三阴性乳腺癌的EMT和转移

miR-124 regulates EMT based on ZEB2 target to inhibit invasion and metastasis in triple-negative breast cancer

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