CXCR1 expression predicts benefit from tyrosine kinase inhibitors therapy in patients with metastatic renal cell carcinoma

Chen Xiang; Liu Li; Wang Jiajun; Lin Zhiyuan; Xiong Ying; Qu Yang; Wang Zewei; Yang Yuanfeng; Guo Jianming; Xu Jiejie

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CXCR1 expression predicts benefit from tyrosine kinase inhibitors therapy in patients with metastatic renal cell carcinoma

机译：CXCR1表达预测酪氨酸激酶抑制剂治疗转移性肾细胞癌患者的益处

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Purpose: CXCR1 signaling promotes tumor progression in various cancers, and clinical trial has proved efficacy of CXCR1 inhibitor in metastatic breast cancer. Therefore, we investigated the prognostic value of CXCR1 in patients with metastatic renal cell carcinoma (mRCC) receiving tyrosine kinase inhibitors (TKIs) therapy.

机译：目的：CXCR1信号传导促进各种癌症中的肿瘤进展，临床试验已经证明了CXCR1抑制剂在转移性乳腺癌中的功效。因此，我们研究了接受酪氨酸激酶抑制剂（TKIS）治疗的转移性肾细胞癌（MRCC）患者CXCR1的预后价值。

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来源
《Urologic oncology》 |2018年第5期|共7页
作者
Chen Xiang; Liu Li; Wang Jiajun; Lin Zhiyuan; Xiong Ying; Qu Yang; Wang Zewei; Yang Yuanfeng; Guo Jianming; Xu Jiejie;
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作者单位

Fudan Univ Zhongshan Hosp Dept Urol Shanghai 200032 Peoples R China;

Fudan Univ Zhongshan Hosp Dept Urol Shanghai 200032 Peoples R China;

Fudan Univ Zhongshan Hosp Dept Urol Shanghai 200032 Peoples R China;

Fudan Univ Zhongshan Hosp Dept Urol Shanghai 200032 Peoples R China;

Fudan Univ Zhongshan Hosp Dept Urol Shanghai 200032 Peoples R China;

Fudan Univ Zhongshan Hosp Dept Urol Shanghai 200032 Peoples R China;

Fudan Univ Sch Basic Med Sci Dept Biochem &

Mol Biol Shanghai 200032 Peoples R China;

Fudan Univ Zhongshan Hosp Dept Urol Shanghai 200032 Peoples R China;

Fudan Univ Zhongshan Hosp Dept Urol Shanghai 200032 Peoples R China;

Fudan Univ Sch Basic Med Sci Dept Biochem &

Mol Biol Shanghai 200032 Peoples R China;

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原文格式 PDF
正文语种 eng
中图分类泌尿科学（泌尿生殖系疾病）;
关键词
Metastatic renal cell carcinoma; CXCR1; Tyrosine kinase inhibitors; Prognosis; Therapeutic response;

机译：转移性肾细胞癌;CXCR1;酪氨酸激酶抑制剂;预后;治疗反应;

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专利

1. CXCR1 expression predicts benefit from tyrosine kinase inhibitors therapy in patients with metastatic renal cell carcinoma [J] . Chen Xiang, Liu Li, Wang Jiajun, Urologic oncology . 2018,第5期

机译：CXCR1表达预测酪氨酸激酶抑制剂治疗转移性肾细胞癌患者的益处
2. Tumor infiltrating CD19+ B lymphocytes predict prognostic and therapeutic benefits in metastatic renal cell carcinoma patients treated with tyrosine kinase inhibitors [J] . Zhiyuan Lin, Li Liu, Yu Xia, Oncoimmunology. . 2018,第10期

机译：肿瘤浸润CD19 + B淋巴细胞预测酪氨酸激酶抑制剂治疗的转移性肾细胞癌患者的预后和治疗益处
3. Expression of PBRM1 as a prognostic predictor in metastatic renal cell carcinoma patients treated with tyrosine kinase inhibitor [J] . International journal of clinical oncology . 2020,第2期

机译：酪氨酸激酶抑制剂治疗转移性肾细胞癌患者的预测预测因子PBRM1的表达
4. Predictive Efficacy of Low Burden EGFR Mutation Detected by Next-Generation Sequencing on Response to EGFR Tyrosine Kinase Inhibitors in Non-Small-Cell Lung Carcinoma [C] . Yeul Hong Kim, Hye Sook Kim, Jae Sook Sung, Molecular Medicine TRI-CON. . 2014

机译：下一代测序对非小细胞肺癌抗蛋白酶激酶抑制剂进行下一代测序检测的低负荷EGFR突变的预测疗效
5. Methodological Approaches for Conducting Claims-Based Studies in Patients Diagnosed with Metastatic Renal Cell Carcinoma [D] . Chun, Danielle S. 2021

机译：用于诊断转移性肾细胞癌的患者的基于权利要求的基于权利要求的方法论方法
6. Tumor infiltrating CD19+ B lymphocytes predict prognostic and therapeutic benefits in metastatic renal cell carcinoma patients treated with tyrosine kinase inhibitors [O] . Zhiyuan Lin, Li Liu, Yu Xia, 2018

机译：肿瘤浸润的CD19 + B淋巴细胞可预测酪氨酸激酶抑制剂治疗的转移性肾细胞癌患者的预后和治疗益处
7. PD03-12 EXPRESSION OF SETD2 COMBINED WITH PBRM1 AS PROGNOSTIC PREDICTOR IN PATIENTS WITH METASTATIC RENAL CELL CARCINOMA RECEIVING TYROSINE KINASE INHIBITOR [O] . Wen Cai*, Jiwei Huang, Zaoyu Wang, 2019

机译：PD03-12 SetD2的表达与PBRM1相结合，作为术治疗酪氨酸激酶抑制剂的患者预后预测因子

CXCR1 expression predicts benefit from tyrosine kinase inhibitors therapy in patients with metastatic renal cell carcinoma

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