Diagnostic value of combined IQGAP3/BMP4 and IQGAP3/FAM107A expression ratios in urinary cell-free DNA for discriminating bladder cancer from hematuria

Xu Yanjie; Kim Ye-Hwan; Jeong pildu; Piao Xuan-Mei; Byun Young Joon; Kang Ho Won; Kim Won Tae; Lee Jong-Young; Kim Isaac Y.; Moon Sung-Kwon; Choi Yung Hyun; Yun Seok Joong; Kim Wun-Jae

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Diagnostic value of combined IQGAP3/BMP4 and IQGAP3/FAM107A expression ratios in urinary cell-free DNA for discriminating bladder cancer from hematuria

机译：IQGAP3 / BMP4和IQGAP3 / FAM107A表达比在尿液细胞DNA中的诊断值，用于鉴别血尿中的膀胱癌

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Background: Urinary cell-free DNA (ucfDNA) has great potential as a "liquid biopsy" for use in diagnosis of urological cancers. In this study, we compared ucfDNA gene expression levels between patients with bladder cancer (BC) and those with hematuria, and determined whether they could be used as a noninvasive urine-based marker.

机译：背景：无尿细胞DNA（UCFDNA）具有巨大的潜力作为用于诊断泌尿外癌的“液体活组织检查”。在本研究中，我们比较了膀胱癌（BC）和血尿患者之间的UCFDNA基因表达水平，并确定它们是否可以用作非侵入性尿基标志物。

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来源
《Urologic oncology》 |2019年第1期|共11页
作者
Xu Yanjie; Kim Ye-Hwan; Jeong pildu; Piao Xuan-Mei; Byun Young Joon; Kang Ho Won; Kim Won Tae; Lee Jong-Young; Kim Isaac Y.; Moon Sung-Kwon; Choi Yung Hyun; Yun Seok Joong; Kim Wun-Jae;
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作者单位

Chungbuk Natl Univ Dept Urol Coll Med Cheongju South Korea;

Chungbuk Natl Univ Dept Urol Coll Med Cheongju South Korea;

Chungbuk Natl Univ Dept Urol Coll Med Cheongju South Korea;

Chungbuk Natl Univ Dept Urol Coll Med Cheongju South Korea;

Chungbuk Natl Univ Dept Urol Coll Med Cheongju South Korea;

Chungbuk Natl Univ Dept Urol Coll Med Cheongju South Korea;

Chungbuk Natl Univ Dept Urol Coll Med Cheongju South Korea;

Chungbuk Natl Univ Dept Business Data Convergence Cheongju South Korea;

Canc Inst New Jersey Sect Urol Oncol New Brunswick NJ USA;

Chung Ang Univ Dept Food Sci &

Technol Ansung South Korea;

Dong Eui Univ Coll Oriental Med Dept Biochem Busan South Korea;

Chungbuk Natl Univ Dept Urol Coll Med Cheongju South Korea;

Chungbuk Natl Univ Dept Urol Coll Med Cheongju South Korea;

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原文格式 PDF
正文语种 eng
中图分类泌尿科学（泌尿生殖系疾病）;
关键词
Urinary cell-free DNA; Biomarker; Discriminant analysis; Bladder cancer; Hematuria;

机译：无细胞的DNA;生物标志物;判别分析;膀胱癌;血尿;

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专利

1. Diagnostic value of combined IQGAP3/BMP4 and IQGAP3/FAM107A expression ratios in urinary cell-free DNA for discriminating bladder cancer from hematuria [J] . Xu Yanjie, Kim Ye-Hwan, Jeong pildu, Urologic oncology . 2019,第1期

机译：IQGAP3 / BMP4和IQGAP3 / FAM107A表达比在尿液细胞DNA中的诊断值，用于鉴别血尿中的膀胱癌
2. Expression and diagnostic value of CCT3 and IQGAP3 in hepatocellular carcinoma [J] . E-Na Qian, Shuang-Yin Han, Song-Ze Ding, Cancer Cell International . 2016,第1期

机译：CCT3和IQGAP3在肝细胞癌中的表达及诊断价值
3. High expression of IQGAP3 indicates poor prognosis in colorectal cancer patients [J] . Jian Wu, Zhen Chen, Huihua Cao, The International journal of biological markers . 2019,第4期

机译：IQGAP3的高表达表明结肠直肠癌患者的预后差
4. Artificial Intelligence Technique for Gene Expression Profiling of Urinary Bladder Cancer [C] . M. F. Abbod, J. W. F. Catto, D. A. Linkens, International IEEE Conference Intelligent Systems . 2006

机译：膀胱癌基因表达探析的人工智能技术
5. Urinary cell-free nucleic acid IQGAP3: a new non-invasive diagnosticmarker for bladder cancer [O] . Won Tae Kim, Ye Hwan Kim, Pildu Jeong, 2018

机译：尿液无细胞核酸IQGAP3：一种新的非侵入性诊断膀胱癌的标志
6. Reduced expression of IQGAP2 and higher expression of IQGAP3 correlates with poor prognosis in cancers. [O] . Dinesh Kumar, Md Khurshidul Hassan, Niharika Pattnaik, 2017

机译：IQGap2的表达降低和IQGap3的高表达与癌症预后不良相关。

Diagnostic value of combined IQGAP3/BMP4 and IQGAP3/FAM107A expression ratios in urinary cell-free DNA for discriminating bladder cancer from hematuria

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