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Childhood trauma and the likelihood of increased suicidal risk in schizophrenia

机译:童年创伤与精神分裂症的自杀风险增加的可能性

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摘要

The aims of the present study were to investigate the dimensions of childhood trauma (CT) in patients with schizophrenia, and to predict suicidal risk (e.g., current suicidal ideation and lifetime suicide attempts) by CT dimensions and clinical factors (positive and negative symptoms and depression). Eighty-two inpatients with schizophrenia completed the Childhood Trauma Questionnaire-Short Form (CTQ-SF), the Beck Depression Inventory-II (BDI-II), and the Beck Scale for Suicide Ideation (BSSI); they were also administered the Positive and Negative Syndrome Scale (PANSS).The presence of lifetime suicide attempts was assessed by structured diagnostic clinical interview. Patients with lifetime suicide attempts scored higher on sexual abuse than those without attempts after controlling for depression severity. Patients with high suicidal risk had higher scores on physical neglect than those without high risk after controlling for depression severity. Patients with high CT had higher scores on negative and positive symptoms, current suicidal ideation, and depression than those with low CT. Logistic regression analyses indicated that sexual abuse was a unique predictor of lifetime suicide attempts, and that physical neglect and depression were unique predictors of current suicidal ideation. These findings indicate that patients with schizophrenia who have experienced CT may be at increased risk for suicide.
机译:本研究的目的是探讨精神分裂症患者儿童创伤(CT)的尺寸,并通过CT尺寸和临床因素预测自杀风险(例如,当前的自杀念头和终身自杀企图)(阳性和阴性症状和沮丧)。有八十二个与精神分裂症的住院患者完成了儿童创伤问卷 - 短表(CTQ-SF),Beck Depression-II(BDI-II),以及自杀式雕刻(BSSI)的贝克规模;它们也被施用了正综合征尺度(平底锅)。通过结构化诊断临床访谈评估了终身自杀企图的存在。终身自杀的患者在控制抑郁严重程度后没有尝试的情况下得分更高。在控制抑郁症严重程度后,患有高自杀风险的患者的身体疏忽比没有高风险的患者。高CT患者对阴性和阳性症状的分数较高,目前的自杀性肌肌瘤和抑郁症比具有低CT的抑郁症。 Logistic回归分析表明,性滥用是一生自杀企图的独特预测因子,身体疏忽和抑郁是当前自杀意念的独特预测因子。这些发现表明,有经历过CT的精神分裂症的患者可能会增加自杀的风险。

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