Pharmacokinetic considerations in antipsychotic augmentation strategies: How to combine risperidone with low-potency antipsychotics

Paulzen Michael; Schoretsanitis Georgios; Stegmann Benedikt; Hiemke Christoph; Griuender Gerhard; Schruers Koen R. J.; Walther Sebastian; Lammertz Sarah E.; Haen Ekkehard

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Pharmacokinetic considerations in antipsychotic augmentation strategies: How to combine risperidone with low-potency antipsychotics

机译：抗精神病药增强策略中的药代动力学考虑因素：如何将Risperidone与低效力抗精神病学结合

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Objectives: To investigate in vivo the effect of low-potency antipsychotics on metabolism of risperidone (RIS).

机译：目的：探讨体内低效力抗精神病药对蓖麻籽酮（RIS）新陈代谢的影响。

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来源
《Progress in Neuro-Psychopharmacology & Biological Psychiatry: An International Research, Review and News Journal》 |2017年第2017期|共6页
作者
Paulzen Michael; Schoretsanitis Georgios; Stegmann Benedikt; Hiemke Christoph; Griuender Gerhard; Schruers Koen R. J.; Walther Sebastian; Lammertz Sarah E.; Haen Ekkehard;
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作者单位

Rhein Westfal TH Aachen Dept Psychiat Psychotherapy &

Psychosomat Pauwelsstr 30 D-52074 Aachen;

Rhein Westfal TH Aachen Dept Psychiat Psychotherapy &

Psychosomat Pauwelsstr 30 D-52074 Aachen;

Univ Regensburg Dept Pharmacol &

Toxicol Regensburg Germany;

Univ Med Ctr Mainz Dept Psychiat &

Psychotherapy Mainz Germany;

Rhein Westfal TH Aachen Dept Psychiat Psychotherapy &

Psychosomat Pauwelsstr 30 D-52074 Aachen;

Maastricht Univ Sch Mental Hlth &

Neurosci Fac Hlth Med &

Life Sci Maastricht Netherlands;

Univ Hosp Psychiat Bern Switzerland;

Rhein Westfal TH Aachen Dept Psychiat Psychotherapy &

Psychosomat Pauwelsstr 30 D-52074 Aachen;

Univ Regensburg Dept Psychiat &

Psychotherapy Clin Pharmacol Regensburg Germany;

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原文格式 PDF
正文语种 eng
中图分类精神病学;
关键词
Antipsychotics; Risperidone; Psychopharmacology; Pharmacokinetics; Therapeutic drug monitoring;

机译：抗精神病药;risperidone;精神掌学;药代动力学;治疗药物监测;

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专利

1. Pharmacokinetic considerations in antipsychotic augmentation strategies: How to combine risperidone with low-potency antipsychotics [J] . Paulzen Michael, Schoretsanitis Georgios, Stegmann Benedikt, Progress in Neuro-Psychopharmacology & Biological Psychiatry: An International Research, Review and News Journal . 2017,第期

机译：抗精神病药增强策略中的药代动力学考虑因素：如何将Risperidone与低效力抗精神病学结合
2. Pharmacokinetic Profile and Clinical Efficacy of Long-Acting Risperidone Potential Benefits of Combining an Atypical Antipsychotic and a New Delivery System [J] . Larry Ereshefsky, Erik Mannaert Drugs in R&D . 2005,第3期

机译：非典型抗精神病药和新的给药系统相结合的长效利培酮酮的药代动力学概况和临床疗效
3. Antipsychotic switching versus augmentation among early non-responders to risperidone or olanzapine in acute-phase schizophrenia [J] . HattaK., OtachiT., FujitaK., Schizophrenia research . 2014,第1a3期

机译：急性期精神分裂症早期对利培酮或奥氮平无反应的抗精神病药转换与增强
4. BINDING STUDIES OF ANTIPSYCHOTIC DRUG RISPERIDONE WITH β-LACTOGLOBULIN USING FLUORIMETRY AND MOLECULAR MODELLING [C] . Bandoo C.Chatale, Laxmi Ananthanarayan, Mariam S.Degani Conference on Drug Design and Discovery Technologies . 2020

机译：用荧光测定和分子造型用β-乳酰叶蛋白抗精神病药立酮的结合研究
5. A Roadmap for Development of Novel Antipsychotic Agents Based on a Risperidone Scaffold. [D] . Shah, Urjita H. 2017

机译：基于利培酮骨架的新型抗精神病药开发路线图。
6. Switching and augmentation strategies for antipsychotic medications in acute-phase schizophrenia: latest evidence and place in therapy [O] . Kotaro Hatta, Naoya Sugiyama, Hiroto Ito 2018

机译：急性期精神分裂症中抗精神病药物的转换和增强策略：最新证据和治疗方法
7. Antipsychotic switching versus augmentation among early non-responders to risperidone or olanzapine in acute-phase schizophrenia [O] . Hatta Kotaro, Otachi Taro, Fujita Kiyoshi, 2014

机译：急性期精神分裂症对利培酮或奥氮平的早期无反应者中抗精神病药转换与增强

Pharmacokinetic considerations in antipsychotic augmentation strategies: How to combine risperidone with low-potency antipsychotics

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