Pentosan polysulfate initiates prion fibrillization by inducing intramolecular, hydrophobic interactions of the octarepeat with the C-terminus

Windsor Martin; Carol Hernan; Cullis-Hill David

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Pentosan polysulfate initiates prion fibrillization by inducing intramolecular, hydrophobic interactions of the octarepeat with the C-terminus

机译：戊磺酸聚硫酸盐通过诱导八烯糖的分子内，与C-末端的分子内疏水相互作用引发朊病毒原纤维

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来源
《Prion》 |2015年第1期|共2页
作者
Windsor Martin; Carol Hernan; Cullis-Hill David;
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Sylvan Sci Sydney NSW Australia;

Sylvan Sci Sydney NSW Australia;

Sylvan Sci Sydney NSW Australia;

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原文格式 PDF
正文语种 eng
中图分类基础医学;
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专利

1. Pentosan polysulfate initiates prion fibrillization by inducing intramolecular, hydrophobic interactions of the octarepeat with the C-terminus [J] . Windsor Martin, Carol Hernan, Cullis-Hill David Prion . 2015,第Suppla1期

机译：戊聚糖多硫酸盐通过诱导八边形与C端的分子内疏水相互作用来引发病毒原纤维化。
2. Differential effects of anti-prion treatments highlight differences in the pathogenesis of sporadic and familial forms of prion disease and identifies novel mode of action for pentosan polysulfate [J] . Lawson Victoria A., Ellett Laura J., Welton Jeremy M., Prion . 2016,第Suppla1期

机译：抗-病毒治疗的不同作用突出了零星和家族形式的ion病毒疾病的发病机理差异，并确定了戊聚糖多硫酸盐的新作用方式
3. Protease-resistant PrP and PrP oligomers in the brain in human prion diseases after intraventricular pentosan polysulfate infusion [J] . HondaH., SasakiK., MinakiH., Neuropathology: official journal of the Japanese Society of Neuropathology . 2012,第2期

机译：脑室内注射戊聚糖多硫酸盐后人病毒病中脑中蛋白酶抗性的PrP和PrP寡聚体
4. Why Is the C-terminus of Aβ(1-42) More Unfolded than That of Aβ(1-40)? Clues from Hydrophobic Interaction [C] . Liang Shen, Hong-Fang Ji, Hong-Yu Zhang 第四届国际分子模拟与信息技术应用学术会议（The 4th International Conference of Molecular Simulations and Applied Informatics Technologies）论文集 . 2008

机译：为什么Aβ（1-42）的C末端比Aβ（1-40）的C末端更展开？疏水相互作用的线索
5. The influence of inter- and intramolecular hydrogen-bonding interactions of azo dyes on the dynamics of photo-induced anisotropy. [D] . Lo, Yu-An. 2013

机译：偶氮染料的分子间和分子内氢键相互作用对光致各向异性动力学的影响。
6. Comparison of the Anti-Prion Mechanism of Four Different Anti-Prion Compounds Anti-PrP Monoclonal Antibody 44B1 Pentosan Polysulfate Chlorpromazine and U18666A in Prion-Infected Mouse Neuroblastoma Cells [O] . Takeshi Yamasaki, Akio Suzuki, Rie Hasebe, -1

机译：Pri病毒感染的小鼠成神经细胞瘤细胞中四种不同抗-药化合物抗PrP单克隆抗体44B1多聚糖戊聚糖氯丙嗪和U18666A的抗Pri药机理的比较
7. Comparison of the anti-prion mechanism of four different anti-prion compounds, anti-PrP monoclonal antibody 44B1, pentosan polysulfate, chlorpromazine, and U18666A, in prion-infected mouse neuroblastoma cells. [O] . Takeshi Yamasaki, Akio Suzuki, Rie Hasebe, 2014

机译：比较四种不同抗朊病毒化合物，抗prp单克隆抗体44B1，戊聚糖多硫酸盐，氯丙嗪和U18666a在朊病毒感染的小鼠成神经细胞瘤细胞中的抗朊病毒机制。

Pentosan polysulfate initiates prion fibrillization by inducing intramolecular, hydrophobic interactions of the octarepeat with the C-terminus

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