Physico-chemical stability of Plasma-Lyte 148 (R) and Plasma-Lyte 148 (R)+5% Glucose with eight common intravenous medications

摘要

Background: Plasma-Lyte 148 (R) is a balanced, crystalloid intravenous (IV) fluid which is both calcium-free and isotonic. It prevents the hyperchloremic metabolic acidosis and iatrogenic hyponatremia seen with use of 0.9% sodium chloride and hypotonic solutions, respectively. However, data on compatibility with commonly used drugs are lacking.