PET-Computed Tomography and PET-MR Imaging and Their Applications in the Twenty-First Century

摘要

Since the discovery of x-ray by Roentgen in 1895, planar radiography has remained a major imaging technique in assessing skeletal abnormalities with reasonable success. However, poor contrast between diseased sites and the background results in low sensitivity of this modality in detecting early disease and monitoring its course over time. The introduction of computed tomography (CT) in 1971 by Hounsfield further enhanced the role of x-ray-based disease assessment, and as such, XCT has played an important role in the day-to-day management of musculoskeletal (MSK) disorders. Since the early 1980s, when the first MR imaging instruments were introduced for human studies, the impact of imaging for examining soft tissue abnormalities in MSK disorders has been substantially enhanced.