Investigations on the viscoelastic performance of pressure sensitive adhesives in drug-in-adhesive type transdermal films.

摘要

Drug solubility parameters and molar drug concentrations have an impact on rheological patterns and thus on the adhesive performance of tested pressure sensitive adhesives intended for use in transdermal drug delivery systems. Use of the Flory equation in its limiting form was appropriate to predict drug solubility in the tested formulations.