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首页> 外文期刊>Pharmaceutical Chemistry Journal >Mechanical and Physical-Technological Properties of Gelatin Ribbon in the Manufacture of Soft Gelatin Capsules
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Mechanical and Physical-Technological Properties of Gelatin Ribbon in the Manufacture of Soft Gelatin Capsules

机译:柔软明胶胶囊制造中明胶色带的机械和物理学性质

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摘要

The mechanical properties of gelatin ribbon and the rheology of bulk gelatin in the manufacture of soft gelatin capsules were studied. The results provide evidence that retention of the strength and elasticity of capsule casings during the manufacturing process and storage requires Young's modulus of the gelatin ribbon to be in the range 35 - 50 MPa, the elongation at breaking being 210 - 240% and the tensile strength being 8 - 9 MPa. The studies also showed that regenerated gelatin stock loses its structural-mechanical properties, particularly its strength and plasticity, which can lead to failure of gelatin capsules during storage and drying.
机译:研究了明胶色带的力学性能和散装明胶在软明胶胶囊制备中的流变学。 结果提供了证据表明,在制造过程和储存期间保留胶囊外壳的强度和弹性需要明胶丝带的杨氏模量在35-50MPa的范围内,伸长率为210-240%和拉伸强度 是8 - 9 mpa。 研究还表明,再生明胶储备失去了其结构 - 机械性能,特别是其强度和可塑性,这可能导致明胶胶囊在储存和干燥过程中的衰竭。

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