DEVELOPMENT OF A CHROMATOGRAPHIC METHOD FOR QUANTITATIVE ANALYSIS OF PHENIBUT IN BIOLOGICAL SAMPLES

I. N. Tyurenkov; V. N. Perfilova; L. A. Smirnova; A. F. Ryabukha; E. A. Suchkov; S. A. Lebedeva

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DEVELOPMENT OF A CHROMATOGRAPHIC METHOD FOR QUANTITATIVE ANALYSIS OF PHENIBUT IN BIOLOGICAL SAMPLES

机译：生物样品中苯纤维定量分析的色谱法

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An ion-pair chromatography method is developed using a reversed-phase C18 column with UV detection for the quantitative analysis of phenibut. The proposed method possesses sufficient selectivity and high sensitivity that enable its effective use during pharmacokinetic studies of phenibut in addition to other GAB A derivatives in biological samples.

机译：使用具有UV检测的反相C18柱开发离子对色谱法，用于定量分析苯bibut。该方法具有足够的选择性和高敏感性，使其在除其他GAB在生物样品中的衍生物之外的苯bibut的药代动力学研究中有效使用。

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来源
《Pharmaceutical Chemistry Journal》 |2010年第12期|共3页
作者
I. N. Tyurenkov; V. N. Perfilova; L. A. Smirnova; A. F. Ryabukha; E. A. Suchkov; S. A. Lebedeva;
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作者单位

Volgograd State Medical University Volgograd Russia.;

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原文格式 PDF
正文语种 eng
中图分类药学;
关键词
phenibut; quantitative analysis; HPLC.;

机译：苯bibut;定量分析;HPLC。;

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专利

1. DEVELOPMENT OF A CHROMATOGRAPHIC METHOD FOR QUANTITATIVE ANALYSIS OF PHENIBUT IN BIOLOGICAL SAMPLES [J] . I. N. Tyurenkov, V. N. Perfilova, L. A. Smirnova, Pharmaceutical Chemistry Journal . 2011,第12期

机译：用于生物样品中苯酚定量分析的色谱方法的建立
2. Chromatographic and mass spectrometric methods for quantitative determination of 3-nitrotyrosine in biological samples and their application to human samples [J] . Henrik Ryberg, Kenneth Caidahl Journal of chromatography, B. Analytical technologies in the biomedical and life sciences . 2007,第1a2期

机译：色谱和质谱法定量测定生物样品中的3-硝基酪氨酸及其在人体样品中的应用
3. Quantitative analysis for organic acids in biological samples: batch isolation followed by gas chromatographic-mass spectrometric analysis. [J] . E Blum-Hoffmann, G Hoffmann, L Sweetman, Clinical Chemistry: Journal of the American Association for Clinical Chemists . 1989,第4期

机译：定量分析生物样品中的有机酸：分批分离，然后进行气相色谱-质谱分析。
4. RECENT ADVANCES IN THE DEVELOPMENT OF EXTRACTION CHROMATOGRAPHIC MATERIALS FOR THE ISOLATION OF RADIONUCLIDES FROM BIOLOGICAL AND ENVIRONMENTAL SAMPLES [C] . ML Dietz, EP Horwitz, R Chiarizia International solvent extraction conference . 2001

机译：从生物和环境样品中分离放射性核素的提取色谱材料的最新进展
5. Development of microanalytical methods for solving sample limiting biological analysis problems. [D] . Metto, Eve C. 2013

机译：解决样品限制的生物学分析问题的微观分析方法的发展。
6. Development and validation of a high-performance thin-layer chromatographic method for the quantitative analysis of vitexin in Passiflora foetida herbal formulations [O] . Ahmed Ibrahim Foudah, Prawez Alam, Y.T. Kamal, 2019

机译：高效薄层色谱法在西番莲中草药制剂中葡萄黄素定量分析的开发和验证
7. Kromatográfiás, kapilláris elektroforetikus és termikus módszerek kidolgozása biológiai és környezeti minták speciációs analízisére = Development of chromatographic, capillary electrophoretic and thermochemical methods for speciation analysis of biological and environmental samples [O] . Posta József, Braun Mihály, Gáspár Attila 2007

机译：用于生物和环境样品形态分析的色谱，毛细管电泳和热化学方法的发展=用于生物和环境样品形态分析的色谱，毛细管电泳和热化学方法的发展
8. Analysis of Biologic Samples for Morphine and Morphine-Related Compounds by Gas Chromatographic-Mass Spectrometric Methods. [R] . Horning, E. C., Thenot, J. P., Horning, M. G. 1976

机译：气相色谱 - 质谱法分析吗啡和吗啡相关化合物的生物样品。

DEVELOPMENT OF A CHROMATOGRAPHIC METHOD FOR QUANTITATIVE ANALYSIS OF PHENIBUT IN BIOLOGICAL SAMPLES

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